MEMBRANE STABILIZING ACTIVITY AND ANTIOXIDANT EFFECT OF SIDA CORDATA (BURM F.) BIOSS AND RHODODENDRON ARBOREUM SM. LEAVES

被引:3
|
作者
Kumar, Deepak [1 ]
Arora, Shefali [2 ]
Kumar, Manoj [1 ]
Thakur, Manoj Kumar [1 ]
Singh, Abhay Pratap [1 ]
机构
[1] Dolphin PG Inst Biomed & Nat Sci, Dept Pharmaceut Chem, Dehra Dun, Uttarakhand, India
[2] Univ Petr & Energy Studies, Dept Chem, Dehra Dun, Uttarakhand, India
关键词
Sida cordata; Rhododendron arboreum; DPPH; Membrane Stabilizing activity; Erythrocyte; Ascorbic acid;
D O I
10.13040/IJPSR.0975-8232.5(1).165-70
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Purpose: To investigate membrane stabilizing activity and antioxidant activity off different extracts of leaves of Sida cordata and Rhododendron arboreum. Methods: Preliminary phytochemical analysis of different extracts of leaves of Sida cordata and Rhododendron arboreum were performed for presence of phytoconstituents. In vitro membrane stabilizing activity was done by using RBC membrane stabilising activity and antioxidant activity was done by using DPPH method. Results: Preliminary phytochemical analysis showed that methanol extract are very rich in phytoconstituents as they showed the presence of alkaloid, carbohydrate, glycosides, proteins and amino acid, Phenolic compounds. All extract are investigated for their in vitro membrane stabilizing activity and antioxidant effect. Methanol and acetone extract of Sida cordata and Rhododendron arboreum showed maximum effect in comparison with other extracts. Conclusion: From the above study it could be concluded that the leaves of Sida cordata and Rhododendron arboreum showed protective effect on inflammation and oxidant.
引用
收藏
页码:165 / 170
页数:6
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