CITBISMINE-A, CITBISMINE-B AND CITBISMINE-C, NEW BINARY ACRIDONE ALKALOIDS FROM CITRUS PLANTS

被引：0

作者：

TAKEMURA, Y

MATSUSHITA, Y

NAGAREYA, N

ABE, M

TAKAYA, J

JUICHI, M

HASHIMOTO, T

KAN, Y

TAKAOKA, S

ASAKAWA, Y

OMURA, M

ITO, C

FURUKAWA, H

机构：

[1] MEIJI UNIV, FAC PHARM, TEMPA KU, NAGOYA, AICHI 468, JAPAN

[2] MUKOGAWA WOMENS UNIV, FAC PHARMACEUT SCI, NISHINOMIYA, HYOGO 663, JAPAN

[3] TOKUSHIMA BUNRI UNIV, FAC PHARMACEUT SCI, TOKUSHIMA 770, JAPAN

[4] MINIST AGR FORESTRY & FISHERIES, FRUIT TREE RES STN, SHIMIZU, SHIZUOKA 42402, JAPAN

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1995年 / 43卷 / 08期

关键词：

CITBISMINE-A; CITBISMINE-B; CITBISMINE-C; BISACRIDONE ALKALOID; CITRUS PARADISI; CITRUS GRANDIS;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three novel dimeric acridone alkaloids named citbismine-A (1), -B (3) and -C (5) have been isolated from the roots of Marsh grapefruit (Citrus paradisi) and Hirado-buntan (C. grandis). The structure of citbismine-A was elucidated as 1 by spectroscopic studies and single crystal X-ray analysis. Structure assignments of citbismine-B (3) and -C (5) were based on spectroscopic data including two dimensional (2D)-NMR (correlation spectroscopy (COSY) and heteronuclear multiple bond correlation (HMBC)) experiments. The common structural characteristic is the presence of a C-C bond between the aromatic ring and the dihydrofuran ring of each acridone nucleus.

引用

页码：1340 / 1345

页数：6

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