DIAGNOSTIC-SIGNIFICANCE OF PROSTATE-SPECIFIC ANTIGEN AND THE DEVELOPMENT OF A MASS-SCREENING SYSTEM FOR PROSTATE-CANCER

被引：44

作者：

IMAI, K ^{[1
]}

ICHINOSE, Y ^{[1
]}

KUBOTA, Y ^{[1
]}

YAMANAKA, H ^{[1
]}

SATO, J ^{[1
]}

机构：

[1] GUNMA CANC CTR HOSP,GUNMA,JAPAN

来源：

JOURNAL OF UROLOGY | 1995年 / 154卷 / 03期

关键词：

ANTIGENS; NEOPLASM; PROSTATIC NEOPLASMS; DIAGNOSIS; DIAGNOSTIC TESTS; ROUTINE;

D O I：

10.1016/S0022-5347(01)66983-0

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose: The significance of prostate specific antigen (PSA) in the mass screening for prostate cancer was investigated. Materials and Methods: A total of 4,375 PSA, digital rectal and transrectal ultrasonographic examinations was performed on 3,526 subjects. Results: Among the 3 modalities, PSA had the highest sensitivity (80.4%) and positive predictive value (45.1%). We established age-specific reference PSA ranges for normal Japanese men, and demonstrated the significance of PSA density and PSA velocity. Conclusions: The significance of PSA as a prostate cancer screening modality should be evaluated across multiple age ranges and in combination with previous PSA data and/or prostate volume.

引用

页码：1085 / 1089

页数：5

共 21 条

[1]

BENSON MC, 1993, J UROLOGY, V147, P815

[2] SCREENING FOR PROSTATIC-CARCINOMA WITH PROSTATE-SPECIFIC ANTIGEN - RESULTS OF THE 2ND-YEAR [J].