UPTAKE AND DIFFUSION OF PHARMACEUTICAL INNOVATIONS IN HEALTH SYSTEMS

被引:10
作者
Atun, Rifat A. [1 ]
Gurol-Urganci, Ipek [1 ]
Sheridan, Desmond [2 ,3 ,4 ,5 ]
机构
[1] Imperial Coll London, Ctr Hlth Management, Tanaka Business Sch, South Kensington Campus, London SW7 2AZ, England
[2] Imperial Coll London, Dept Natl Heart, London W2 1PG, England
[3] Imperial Coll London, Lung Inst, London W2 1PG, England
[4] St Marys Hosp, Dept Natl Heart, London W2 1PG, England
[5] St Marys Hosp, Lung Inst, London W2 1PG, England
关键词
Diffusion of innovation; pharmaceuticals; regulatory environment;
D O I
10.1142/S1363919607001709
中图分类号
C93 [管理学];
学科分类号
12 ; 1201 ; 1202 ; 120202 ;
摘要
Multiple interacting factors influence the uptake and diffusion of medicines which are critical to improving health. However, there is a gap in our knowledge on how regulatory policies and other national health systems attributes combine to impact on the utilisation of innovative drugs, and health system goals and objectives. Our review demonstrates that strong regulation adversely affects access to innovation, reduces incentives for research-based firms to develop innovative products and leads to short-and long-term welfare losses. Short-term efficiency gains from reducing pharmaceutical expenditures may actually increase total healthcare costs, reduce user choice, and in some cases, adversely affect health outcomes. Decision makers need to adopt a holistic approach to policy making, and consider potential impact of regulations on the uptake and diffusion of innovations, innovation systems and health system goals.
引用
收藏
页码:299 / 321
页数:23
相关论文
共 137 条
[31]   The price of innovation: new estimates of drug development costs [J].
DiMasi, JA ;
Hansen, RW ;
Grabowski, HG .
JOURNAL OF HEALTH ECONOMICS, 2003, 22 (02) :151-185
[32]  
DOR A, 2004, 10738 NBER
[33]   International comparison of the definition and the practical application of health technology assessment [J].
Draborg, E ;
Gyrd-Hansen, D ;
Poulsen, PB ;
Horder, M .
INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE, 2005, 21 (01) :89-95
[34]   REPORT OF THE TASK-FORCE ON THE AVAILABILITY OF CARDIOVASCULAR DRUGS TO THE MEDICALLY INDIGENT [J].
DUSTAN, HP ;
CAPLAN, LR ;
CURRY, CL ;
DELEON, AC ;
DOUGLAS, FL ;
FRISHMAN, W ;
HILL, MN ;
WASHINGTON, RL ;
STEIGERWALT, S ;
SHULMAN, NB ;
TAUBERT, KA ;
CHAMPAGNE, B ;
GROOM, A .
CIRCULATION, 1992, 85 (02) :849-860
[36]   Characteristics of demand for pharmaceutical products: an examination of four cephalosporins [J].
Ellison, SF ;
Cockburn, I ;
Griliches, Z ;
Hausman, J .
RAND JOURNAL OF ECONOMICS, 1997, 28 (03) :426-446
[37]   The new pharmaceutical policy in Italy [J].
Fattore, G ;
Jommi, C .
HEALTH POLICY, 1998, 46 (01) :21-41
[38]  
Ferlie E, 2000, J Health Serv Res Policy, V5, P96
[39]   Innovation in healthcare: how does credible evidence influence professionals? [J].
Fitzgerald, L ;
Ferlie, E ;
Hawkins, C .
HEALTH & SOCIAL CARE IN THE COMMUNITY, 2003, 11 (03) :219-228
[40]   Utilization of essential medications by vulnerable older people after a drug benefit cap: Importance of mental disorders, chronic pain, and practice setting [J].
Fortess, EE ;
Soumerai, SB ;
McLaughlin, TJ ;
Ross-Degnan, D .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2001, 49 (06) :793-797