VITAL COMPUTER MORPHOMETRY OF LIMPHOCYTES IN DIAGNOSIS OF ACUTE RENAL ALLOGRAFT REJECTION

被引:0
作者
Vatazin, A. V. [1 ]
Vasilenko, I. A. [2 ]
Valov, A. L. [3 ]
Metelin, V. B. [2 ]
Kruglov, E. E. [1 ]
Tsalman, A. Ya [1 ]
机构
[1] MF Vladimirsky Moscow Reg Res Clin Inst, Moscow, Russia
[2] Russian Res Clin Ctr Gerontol, Moscow, Russia
[3] Russian Children Clin Hosp, Moscow, Russia
来源
VESTNIK TRANSPLANTOLOGII I ISKUSSTVENNYH ORGANOV | 2009年 / 11卷 / 04期
关键词
renal transplantation; acute allograft rejection; lymphocytes; morphometry;
D O I
暂无
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
The article focuses on the results of the investigation of peripheral blood lymphocyte morphofunctional status in healthy volunteers and renal allograft recipients for early postoperative period. Working out noninvasive tests for diagnosis of acute renal allograft rejection based on the measuring of cell morphometric parameters by method of coherent phase microscopy (CPM). It was found out that the lymphocyte phase height was proportional cell image density and its geometrical thickness. Our results showed that the variations of immunocompetent cell morphometric indicants can be in advance the dynamics of blood creatine increasing and answer for early criteria of acute renal allograft rejection.
引用
收藏
页码:18 / 25
页数:8
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