DIAGNOSIS AND THERAPY IN CHRONIC HEPATITIS-B VIRUS-INFECTION .2. ALFA - INTERFERON - EFFECTIVE TREATMENT OF CHRONIC HEPATITIS-B

被引：0

作者：

JANSSEN, HLA ^{[1
]}

DEMAN, RA ^{[1
]}

SCHALM, SW ^{[1
]}

机构：

[1] ACAD ZIEKENHUIS DIJKZIGT ROTTERDAM,INWENDIGE GENEESKUNDE POLIKLIN 2,SECTIE HEPATOL,3015 GD ROTTERDAM,NETHERLANDS

来源：

TGO-TIJDSCHRIFT VOOR THERAPIE GENEESMIDDEL EN ONDERZOEK JDR-JOURNAL FOR DRUGTHERAPY AND RESEARCH | 1992年 / 17卷 / 04期

关键词：

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Alfa-interferon (alpha-IFN) has now proven to be an effective treatment for HBeAg-positive patients with chronic hepatitis B. In approximately one third of the patients alpha-IFN induces a transition to viral latency (HBeAg seroconversion) which is almost always followed by a disappearance of inflammatory activity. Progression of the disease is then arrested. Patients should preferably be monitored in regional centers since a severe exacerbation of the liver disease con occur and neuropsychiatric side effects of alpha-IFN calls for expertise in management. For chronic hepatitis B patients with decompensated liver disease or co-infection with the hepatitis delta virus the benefit-risk ratio of alpha-IFN still needs to be established.

引用

页码：113 / 115

页数：3