REPORT OF THE AMERICAN-EUROPEAN CONSENSUS CONFERENCE ON ACUTE RESPIRATORY-DISTRESS SYNDROME - DEFINITIONS, MECHANISMS, RELEVANT OUTCOMES, AND CLINICAL-TRIAL COORDINATION

被引:292
作者
BERNARD, GR [1 ]
ARTIGAS, A
BRIGHAM, KL
CARLET, J
FALKE, K
HUDSON, L
LAMY, M
LEGALL, JR
MORRIS, A
SPRAGG, R
Cochin, B
Lanken, PN
Leeper, KV
Marini, J
Murray, JF
Oppenheimer, L
Pesenti, A
Reid, L
Rinaldo, J
Villar, J
van Asbeck, BS
Dhainaut, JF
Mancebo, J
Matthay, M
Meyrick, B
Payen, D
Perret, C
Fowler, AA
Schaller, MD
Hudson, LD
Hyers, T
Knaus, W
Matthay, R
Pinsky, M
Bone, RC
Bosken, C
Johanson, WG
Lewandowski, K
Repine, J
Rodriguez-Roisin, R
Roussos, C
Antonelli, MA
Beloucif, S
Bihari, D
Burchardi, H
LeMaire, F
Montravers, P
Petty, TL
Robotham, J
Zapol, W
机构
[1] VANDERBILT UNIV, T-1219 MCN, NASHVILLE, TN 37232 USA
[2] Latter Day St Hosp, Salt Lake City, UT USA
[3] St Josephs Hosp, Paris, FRANCE
[4] Hosp Paris, Paris, FRANCE
[5] Univ Penn, Philadelphia, PA 19104 USA
[6] Univ Tennessee, Memphis, TN USA
[7] Univ Minnesota, Minneapolis, MN USA
[8] Univ Calif San Francisco, San Francisco, CA 94143 USA
[9] Univ Manitoba, Winnipeg, MB, CANADA
[10] Univ Milan, Monza, ITALY
[11] Harvard Med Sch, Childrens Hosp, Boston, MA 02115 USA
[12] Univ Toronto, Toronto, ON, CANADA
[13] Vanderbilt Univ, Sch Med, Nashville, TN 37212 USA
[14] Univ Liege, Liege, BELGIUM
[15] Univ Utrecht, Utrecht, NETHERLANDS
[16] Cochin Port Royal Univ Hosp, Paris, FRANCE
[17] Hosp Sta Creu I St Pau, Barcelona, SPAIN
[18] Hosp Lariboisiere, Paris, FRANCE
[19] Med Coll Virginia, Richmond, VA USA
[20] Univ Lausanne, Lausanne, SWITZERLAND
[21] Univ Washington, Seattle, WA 98195 USA
[22] St Louis Univ, St Louis, MO 63103 USA
[23] George Washington Univ, Washington, DC USA
[24] Yale Univ, New Haven, CT USA
[25] Univ Pittsburgh, Pittsburgh, PA USA
[26] Univ Calif San Diego, San Diego, CA 92103 USA
[27] Rush Med Coll, Chicago, IL 60612 USA
[28] Natl Heart & Lung Inst, NIH, Div Lung Dis, Bethesda, MD USA
[29] New Jersey Med Sch, Newark, NJ USA
[30] Univ Colorado, Hlth Sci Ctr, Webb Waring Inst Biomed Res, Denver, CO USA
[31] Hosp Clin Barcelona, Barcelona, SPAIN
[32] Evangelismos Hosp, Athens, GREECE
[33] Univ Studi, Rome, ITALY
[34] Guys Hosp, London, ENGLAND
[35] Univ Gottingen, Gottingen, GERMANY
[36] Univ Colorado, Hlth Sci Ctr, Denver, CO USA
[37] Massachusetts Gen Hosp, Boston, MA 02114 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/0883-9441(94)90033-7
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
The acute respiratory distress syndrome (ARDS), a process of nonhydrostatic pulmonary edema and hypoxemia associated with a variety of etiologies, carries a high morbidity rate, mortality rate (10% to 90%), and financial cost. The reported annual incidence in the United States is 150,000 cases, but this figure has been challenged and may be different in Europe. Part of the reason for these uncertainties is the heterogeneity of diseases underlying ARDS and the lack of uniform definitions for ARDS. Thus, those who wish to know the true incidence and outcome of this clinical syndrome are stymied. The European American Consensus Committee on ARDS was formed to focus on these issues and on the pathophysiologic mechanisms of the process. It was felt that international coordination between North America and Europe in clinical studies of ARDS was becoming increasingly important to address the recent plethora of potential therapeutic agents for the prevention and treatment of ARDS. © 1994.
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收藏
页码:72 / 81
页数:10
相关论文
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