IN-VITRO DIFFUSION STUDIES OF KETOPROFEN TRANSDERMAL THERAPEUTIC SYSTEMS

被引:14
作者
VALENTA, C
ALMASISZABO, I
机构
[1] Institute of Pharmaceutical Technology, University of Vienna, Vienna
关键词
D O I
10.3109/03639049509069267
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The release of Ketoprofen from the matrix model of TTS were studied. It may be concluded that the pharmaceutical availability of the drug can be regulated by the type and thickness of the matrix. Quantitation of the active agent in the dissolution medium was done by UV-spectroscopy. The results obtained by the rotating cylinder method were compared to another method utilizing a modified Stricker cell.
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页码:1799 / 1805
页数:7
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