ACUTE TOCOLYSIS FOR FETAL DISTRESS - TERBUTALINE VERSUS MAGNESIUM-SULFATE

被引:21
作者
MAGANN, EF
CLEVELAND, RS
DOCKERY, JR
CHAUHAN, SP
MARTIN, JN
MORRISON, JC
机构
[1] Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Mississippi Medical Center
关键词
D O I
10.1111/j.1479-828X.1993.tb02109.x
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Forty-six women in active labour who developed fetal distress requiring abdominal delivery were randomized to receive 0.25 mg of terbutaline (subcutaneously) or magnesium sulphate as a 4-g bolus (intravenously) to decrease uterine activity. The terbutaline-treated group in contrast to the magnesium sulphate-treated group had reduced uterine activity as measured by Montevideo units (p <0.002). This decrease in uterine activity was noted more rapidly in all 23 patients who received terbutaline, 1.8 +/- 0.74 minutes compared to 7.5 +/- 2.1 minutes in the 16 of 23 patients (magnesium sulphate-treated women) in whom a decrease in uterine activity occurred (p <0.001). Umbilical cord arterial blood pH at delivery was less than 7.20 in only 2 of the 23 patients treated with terbutaline versus 7 of the 23 in the magnesium sulphate-treated group. We conclude that terbutaline is an effective and more rapid-acting tocolytic agent to arrest uterine activity prior to delivery for fetal distress.
引用
收藏
页码:362 / 364
页数:3
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