COMPARISON OF SYNEXIN ISOTYPES IN SECRETORY AND NON-SECRETORY TISSUES

被引：15

作者：

DOWLING, LG

CREUTZ, CE

机构：

[1] UNIV VIRGINIA, PROGRAM NEUROSCI, CHARLOTTESVILLE, VA 22908 USA

[2] UNIV VIRGINIA, PROGRAM BIOPHYS, CHARLOTTESVILLE, VA 22908 USA

[3] UNIV VIRGINIA, PROGRAM CELL & MOLEC BIOL, CHARLOTTESVILLE, VA 22908 USA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1985年 / 132卷 / 01期

关键词：

D O I：

10.1016/0006-291X(85)91033-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three synexin isotypes were identified in bovine liver or adrenal medullary tissues by immune blotting of one- or two-dimensional SDS gels and by two-dimensional tryptic peptide mapping of gel bands or spots. These isotypes were: .alpha.-synexin, mass 47 kDa, pI 6.9; .beta.-synexin, mass 47 kDa, pI 6.5; and .mu.-synexin, mass 51 kDa, pI 6.1. A non-secretory tissues, bovine skeletal muscle, was found to contain only .mu.-synexin. The absence of .alpha.- and .beta.-synexins in a non-secretory tissue suggests these proteins may perform specific roles in the process of exocytosis.

引用

页码：382 / 389

页数：8

共 12 条

[1]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[2]

BURNETTE WN, 1981, ANAL BIOCHEM, V112, P195, DOI 10.1016/0003-2697(81)90281-5

[3]

CALDWELL P C, 1970, P10

[4]

CREUTZ CE, 1984, MET IONS BIOL SYST, V17, P319