MEMBRANE AND NON-MEMBRANE PROTEINS - A COMPARISON

被引:0
作者
Gaur, Rajneesh K. [1 ]
机构
[1] Minist Sci & Technol, Dept Biotechnol, New Delhi 110003, India
关键词
Membrane Proteins; MPs; non-Membrane Proteins; nMPs; Amino acid composition; Prokaryotes; Eukaryotes; Essential amino acids;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Membrane and non-membrane proteins (MPs & nMPs) constitute the total cellular protein content. The correlation between the amino acid composition of these two classes of proteins within the same and different major class of organism is interesting to know. Amino acid composition analysis of two classes of proteins indicates that the prokaryotic and eukaryotic MPs and nMPs are unique. Furthermore, the composition analysis of essential amino acids in prokaryotic and eukaryotic MPs and nMPs shows the occurrence of high overall percentage frequency of essential amino acids in pkMPs. The high occurrence of essential amino acids in pkMPs may be exploited for medicinal purpose.
引用
收藏
页码:12 / 15
页数:4
相关论文
共 19 条
[1]   Protein length in eukaryotic and prokaryotic proteomes [J].
Brocchieri, L ;
Karlin, S .
NUCLEIC ACIDS RESEARCH, 2005, 33 (10) :3390-3400
[2]   Relation between amino acid composition and cellular location of proteins [J].
Cedano, J ;
Aloy, P ;
PerezPons, JA ;
Querol, E .
JOURNAL OF MOLECULAR BIOLOGY, 1997, 266 (03) :594-600
[3]   Prokaryotic and eukaryotic integral membrane proteins have similar architecture [J].
Gaur, Rajneesh Kumar ;
Natekar, Girija Arun .
MOLECULAR BIOLOGY REPORTS, 2010, 37 (03) :1247-1251
[4]   How representative are the known structures of the proteins in a complete genome? A comprehensive structural census [J].
Gerstein, M .
FOLDING & DESIGN, 1998, 3 (06) :497-512
[5]  
Gutierrez-Preciado A., 2010, NAT ED, V3, P29
[6]   Putative Functional Role for the Invariant Aspartate 263 Residue of Rhodospirillum rubrum Rubisco [J].
Liggins, John R. ;
Gready, Jill E. .
BIOCHEMISTRY, 2009, 48 (10) :2226-2236
[7]   OPM: Orientations of proteins in membranes database [J].
Lomize, MA ;
Lomize, AL ;
Pogozheva, ID ;
Mosberg, HI .
BIOINFORMATICS, 2006, 22 (05) :623-625
[8]   Relationship of Sidechain Hydrophobicity and alpha-Helical Propensity on the Stability of the Single-stranded Amphipathic alpha-Helix [J].
Monera, Oscar D. ;
Sereda, Terrance J. ;
Zhou, Nian E. ;
Kay, Cyril M. ;
Hodges, Robert S. .
JOURNAL OF PEPTIDE SCIENCE, 1995, 1 (05) :319-329
[9]   DISCRIMINATION OF INTRACELLULAR AND EXTRACELLULAR PROTEINS USING AMINO-ACID-COMPOSITION AND RESIDUE-PAIR FREQUENCIES [J].
NAKASHIMA, H ;
NISHIKAWA, K .
JOURNAL OF MOLECULAR BIOLOGY, 1994, 238 (01) :54-61
[10]   Classification schemes for protein structure and function [J].
Ouzounis, CA ;
Coulson, RMR ;
Enright, AJ ;
Kunin, V ;
Pereira-Leal, JB .
NATURE REVIEWS GENETICS, 2003, 4 (07) :508-519