PHASE-BEHAVIOR OF MIXTURES OF CHOLESTEROL AND SATURATED PHOSPHATIDYLGLYCEROLS

被引：40
|
作者：
BOROCHOV, N
WACHTEL, EJ
BACH, D
机构：
[1] WEIZMANN INST SCI,DEPT MEMBRANE RES & BIOPHYS,IL-76100 REHOVOT,ISRAEL
[2] CTR TECHNOL EDUC HOLON,HOLON,ISRAEL
来源：
CHEMISTRY AND PHYSICS OF LIPIDS | 1995年 / 76卷 / 01期
关键词：
CHOLESTEROL; PHOSPHATIDYLGLYCEROL; PHOSPHATIDYLCHOLINE; DIFFERENTIAL SCANNING CALORIMETRY; X-RAY DIFFRACTION; BILAYERS;
D O I：
10.1016/0009-3084(94)02411-W
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The interaction of cholesterol with a series of saturated phosphatidylglycerols was investigated using differential scanning calorimetry and X-ray diffraction. We find that the miscibility of cholesterol in phosphatidylglycerol bilayers is lower than in the corresponding phosphatidylcholine bilayers and decreases with increasing acyl chain length of the phospholipid. The influence of the negative charge of the phosphatidylglycerol on cholesterol miscibility is discussed.
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页码：85 / 92
页数：8
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