PHASE-BEHAVIOR OF MIXTURES OF CHOLESTEROL AND SATURATED PHOSPHATIDYLGLYCEROLS

被引：41
作者：
BOROCHOV, N
WACHTEL, EJ
BACH, D
机构：
[1] WEIZMANN INST SCI,DEPT MEMBRANE RES & BIOPHYS,IL-76100 REHOVOT,ISRAEL
[2] CTR TECHNOL EDUC HOLON,HOLON,ISRAEL
来源：
CHEMISTRY AND PHYSICS OF LIPIDS | 1995年 / 76卷 / 01期
关键词：
CHOLESTEROL; PHOSPHATIDYLGLYCEROL; PHOSPHATIDYLCHOLINE; DIFFERENTIAL SCANNING CALORIMETRY; X-RAY DIFFRACTION; BILAYERS;
D O I：
10.1016/0009-3084(94)02411-W
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The interaction of cholesterol with a series of saturated phosphatidylglycerols was investigated using differential scanning calorimetry and X-ray diffraction. We find that the miscibility of cholesterol in phosphatidylglycerol bilayers is lower than in the corresponding phosphatidylcholine bilayers and decreases with increasing acyl chain length of the phospholipid. The influence of the negative charge of the phosphatidylglycerol on cholesterol miscibility is discussed.
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页码：85 / 92
页数：8
相关论文
共 24 条
[1]   PHASE-BEHAVIOR OF HETEROACID PHOSPHATIDYLSERINES AND CHOLESTEROL [J].
BACH, D ;
WACHTEL, E ;
BOROCHOV, N ;
SENISTERRA, G ;
EPAND, RM .
CHEMISTRY AND PHYSICS OF LIPIDS, 1992, 63 (1-2) :105-113
[2]   THERMOTROPIC PROPERTIES OF MIXTURES OF NEGATIVELY CHARGED PHOSPHOLIPIDS WITH CHOLESTEROL IN THE PRESENCE AND ABSENCE OF LI+ OR CA2+ IONS [J].
BACH, D ;
WACHTEL, E .
BIOCHIMICA ET BIOPHYSICA ACTA, 1989, 979 (01) :11-19
[3]   DIFFERENTIAL SCANNING CALORIMETRIC STUDY OF MIXTURES OF CHOLESTEROL WITH PHOSPHATIDYLSERINE OR GALACTOCEREBROSIDE [J].
BACH, D .
CHEMISTRY AND PHYSICS OF LIPIDS, 1984, 35 (04) :385-392
[4]  
BACH D, 1983, BIOMEMBRANE STRUCTUR, P1
[5]   THERMOTROPIC BEHAVIOR OF PHOSPHATIDYLETHANOLAMINE-CHOLESTEROL AND PHOSPHATIDYLETHANOLAMINE-PHOSPHATIDYLCHOLINE-CHOLESTEROL MIXTURES [J].
BLUME, A .
BIOCHEMISTRY, 1980, 19 (21) :4908-4913
[6]   ROLE OF THE STEREOCHEMISTRY OF THE HYDROXYL GROUP OF CHOLESTEROL AND THE FORMATION OF NONBILAYER STRUCTURES IN PHOSPHATIDYLETHANOLAMINES [J].
CHEETHAM, JJ ;
WACHTEL, E ;
BACH, D ;
EPAND, RM .
BIOCHEMISTRY, 1989, 28 (22) :8928-8934
[7]   THE STRUCTURE OF ANHYDROUS AND HYDRATED DIMYRISTOYLPHOSPHATIDYL GLYCEROL - A PRESSURE TUNING INFRARED SPECTROSCOPIC STUDY [J].
CHOMA, CT ;
WONG, PTT .
CHEMISTRY AND PHYSICS OF LIPIDS, 1992, 61 (02) :131-137
[8]   FORMATION OF A NEW STABLE PHASE OF PHOSPHATIDYLGLYCEROLS [J].
EPAND, RM ;
GABEL, B ;
EPAND, RF ;
SEN, A ;
HUI, SW ;
MUGA, A ;
SUREWICZ, WK .
BIOPHYSICAL JOURNAL, 1992, 63 (02) :327-332
[9]   INTERACTION BETWEEN CHOLESTEROL AND PHOSPHOLIPID IN HYDRATED BILAYERS [J].
FINEAN, JB .
CHEMISTRY AND PHYSICS OF LIPIDS, 1990, 54 (3-4) :147-156
[10]   THE SWELLING OF EGG LECITHIN IN WATER [J].
HARBICH, W ;
HELFRICH, W .
CHEMISTRY AND PHYSICS OF LIPIDS, 1984, 36 (01) :39-63
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