CHANGING PATTERNS OF HEPATITIS-A VIRUS-INFECTION IN CHILDREN IN PALERMO, ITALY

被引:19
作者
STROFFOLINI, T
DECRESCENZO, L
GIAMMANCO, A
INTONAZZO, V
LAROSA, G
CASCIO, A
SARZANA, A
CHIARINI, A
DARDANONI, L
机构
[1] Laboratorio di Epidemiologia, Istituto Superiore di Sanitá, Rome, 00161
[2] Istituto di Igiene e Medicina Preventiva, Università di Palermo
[3] Istituto di Microbiologia, Università di Palermo
[4] Clinica di Malattie Infettive, Università di Palermo
关键词
Antibody; Children; Hepatitis A; Infection;
D O I
10.1007/BF00155556
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
In 1988 in Palermo, Italy the prevalence of antibodies to hepatitis A virus (anti-HAV) in a sample of 490 children 6-13 years old was 10.6%; it increased from 6.3% among children 6-10 years old to 14.7% in children 11-13 years old (P < 0.01). Compared with findings from a survey conducted in 1978 in the same area, the results of the present study show a significant (P < 0.01) reduction in the anti-HAV prevalence in both age groups. Anti-HAV prevalence was inversely related to the father's years of education and positively related to the family size. Children of fathers with less than 6 years of schooling had a 3.2-fold risk (C.I. 95% = 1.3-8.1), and children with five or more members in their households had a 2.7-fold risk (C.I. 95% = 1.1-6.4) of previous exposure to hepatitis A virus (HAV) infection. Our findings indicate that exposure of children in Palermo to HAV is decreasing significantly, probably because of improvements in socio-economic conditions during recent years; however socio-demographic factors appear to be important determinants of infection. © 1990 Kluwer Academic Publishers.
引用
收藏
页码:84 / 87
页数:4
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