THE CLINICAL-DIAGNOSIS OF ALZHEIMERS-DISEASE

被引:258
作者
WADE, JPH
MIRSEN, TR
HACHINSKI, VC
FISMAN, M
LAU, C
MERSKEY, H
机构
[1] LONDON PSYCHIAT HOSP, DEPT EDUC & RES,850 HIGHBURY AVE,POB 2532, TERMINAL A, LONDON N6A 4H1, ONTARIO, CANADA
[2] CHARING CROSS HOSP, DEPT NEUROL, LONDON W6 8RP, ENGLAND
[3] UNIV WESTERN ONTARIO HOSP, DEPT CLIN NEUROL SCI, LONDON N6A 5A5, ONTARIO, CANADA
关键词
D O I
10.1001/archneur.1987.00520130016010
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Clinical and pathological diagnoses are compared in 65 patients who had dementia and who had been studied longitudinally during life. The sensitivity of diagnosis for dementia of the Alzheimer type (DAT) without any other diagnosis was 87%, and the specificity was 78%. The ischemic scale score did not discriminate well between patients with pure multi-infarct dementia and those with both DAT and multi-infarct dementia. However, 35 of 38 cases of pure DAT had a score of 4 or less on the ischemic scale.
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页码:24 / 29
页数:6
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