GENE-TRANSFER OF DRUG-RESISTANCE GENES - IMPLICATIONS FOR CANCER-THERAPY

被引：33

作者：

GOTTESMAN, MM ^{[1
]}

GERMANN, UA ^{[1
]}

AKSENTIJEVICH, I ^{[1
]}

SUGIMOTO, Y ^{[1
]}

CARDARELLI, CO ^{[1
]}

PASTAN, I ^{[1
]}

机构：

[1] NCI,MOLEC BIOL LAB,BETHESDA,MD 20892

来源：

GENE THERAPY FOR NEOPLASTIC DISEASES | 1994年 / 716卷

关键词：

D O I：

10.1111/j.1749-6632.1994.tb21708.x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

[No abstract available]

引用

页码：126 / 139

页数：14

共 43 条

[1] THE GENE ENCODING MULTIDRUG RESISTANCE IS INDUCED AND EXPRESSED AT HIGH-LEVELS DURING PREGNANCY IN THE SECRETORY EPITHELIUM OF THE UTERUS [J].

ARCECI, RJ ;

CROOP, JM ;

HORWITZ, SB ;

HOUSMAN, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (12) :4350-4354

[2]

BRUGGEMANN EP, 1992, J BIOL CHEM, V267, P21020

[3] EXPRESSION AND ACTIVITY OF P-GLYCOPROTEIN, A MULTIDRUG EFFLUX PUMP, IN HUMAN HEMATOPOIETIC STEM-CELLS [J].

CHAUDHARY, PM ;

RONINSON, IB .

CELL, 1991, 66 (01) :85-94

[4] INTERNAL DUPLICATION AND HOMOLOGY WITH BACTERIAL TRANSPORT PROTEINS IN THE MDR1 (P-GLYCOPROTEIN) GENE FROM MULTIDRUG-RESISTANT HUMAN-CELLS [J].

CHEN, CJ ;

CHIN, JE ;

UEDA, K ;

CLARK, DP ;

PASTAN, I ;

GOTTESMAN, MM ;

RONINSON, IB .

CELL, 1986, 47 (03) :381-389

[5] AN ALTERED PATTERN OF CROSS-RESISTANCE IN MULTIDRUG-RESISTANT HUMAN-CELLS RESULTS FROM SPONTANEOUS MUTATIONS IN THE MDR1 (P-GLYCOPROTEIN) GENE [J].

CHOI, K ;

CHEN, C ;

KRIEGLER, M ;

RONINSON, IB .

CELL, 1988, 53 (04) :519-529

[6] MULTIDRUG-RESISTANCE GENE (P-GLYCOPROTEIN) IS EXPRESSED BY ENDOTHELIAL-CELLS AT BLOOD-BRAIN BARRIER SITES [J].

CORDONCARDO, C ;

OBRIEN, JP ;

CASALS, D ;

RITTMANGRAUER, L ;

BIEDLER, JL ;

MELAMED, MR ;

BERTINO, JR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (02) :695-698

[7]

CURRIER SJ, 1992, J BIOL CHEM, V267, P25153

[8] AMINO-ACID SUBSTITUTIONS IN THE 6TH TRANSMEMBRANE DOMAIN OF P-GLYCOPROTEIN ALTER MULTIDRUG RESISTANCE [J].

DEVINE, SE ;

LING, V ;

MELERA, PW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (10) :4564-4568

[9] EXPRESSION OF A HUMAN MULTIDRUG RESISTANCE CDNA (MDR1) IN THE BONE-MARROW OF TRANSGENIC MICE - RESISTANCE TO DAUNOMYCIN-INDUCED LEUKOPENIA [J].

GALSKI, H ;

SULLIVAN, M ;

WILLINGHAM, MC ;

CHIN, KV ;

GOTTESMAN, MM ;

PASTAN, I ;

MERLINO, GT .

MOLECULAR AND CELLULAR BIOLOGY, 1989, 9 (10) :4357-4363

[10] HOMOLOGY BETWEEN P-GLYCOPROTEIN AND A BACTERIAL HEMOLYSIN TRANSPORT PROTEIN SUGGESTS A MODEL FOR MULTIDRUG RESISTANCE [J].

GERLACH, JH ;

ENDICOTT, JA ;

JURANKA, PF ;

HENDERSON, G ;

SARANGI, F ;

DEUCHARS, KL ;

LING, V .

NATURE, 1986, 324 (6096) :485-489

← 1 2 3 4 5 →