MOLECULAR-CLONING AND SEQUENCING OF A HUMAN CDNA-ENCODING ORNITHINE DECARBOXYLASE ANTIZYME

被引:24
作者
TEWARI, DS
QIAN, YK
THORNTON, RD
PIERINGER, J
TAUB, R
MOCHAN, E
TEWARI, M
机构
[1] PHILADELPHIA COLL OSTEOPATH MED,DEPT BIOCHEM MOLEC BIOL,PHILADELPHIA,PA 19131
[2] UNIV PENN,SCH MED,DEPT GENET,PHILADELPHIA,PA 19131
来源
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY | 1994年 / 1209卷 / 02期
关键词
ORNITHINE DECARBOXYLASE; POLYAMINES; ORNITHINE DECARBOXYLASE ANTIZYME;
D O I
10.1016/0167-4838(94)90199-6
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We report the cloning of a cDNA encoding the human homolog of ornithine decarboxylase antizyme from a human gingival fibroblast cDNA library. The human antizyme is 84% identical to the rat sequence and shows almost no homology to the E. coli antizyme. Northern analysis studies show that this gene is expressed in both human gingival and synovial fibroblasts.
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页码:293 / 295
页数:3
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