LINKAGE OF A GENE FOR DOMINANT NON-SYNDROMIC DEAFNESS TO CHROMOSOME-19

被引：65
|
作者：
CHEN, AH
NI, L
FUKUSHIMA, K
MARIETTA, J
ONEILL, M
COUCKE, P
WILLEMS, P
SMITH, RJH
机构：
[1] UNIV IOWA,DEPT DERMATOL,MOLEC OTOLARYNGOL RES LABS,IOWA CITY,IA 52242
[2] UNIV ANTWERP,DEPT MED GENET,B-2020 ANTWERP,BELGIUM
来源：
HUMAN MOLECULAR GENETICS | 1995年 / 4卷 / 06期
关键词：
D O I：
10.1093/hmg/4.6.1073
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Inherited hearing impairment can occur either in the presence of other clinical features (syndromic hearing loss, SHL) or in isolation (non-syndromic hearing loss, NSHL), The latter is more common and is highly heterogeneous, To date, six NSHL loci have been mapped, We report the identification of a seventh locus (DFNA4) on chromosome 19q13 and suggest DM kinase as a possible candidate gene.
引用
收藏
页码：1073 / 1076
页数：4
相关论文
共 50 条
  • [1] Non-syndromic autosomal-dominant deafness
    Petersen, MB
    CLINICAL GENETICS, 2002, 62 (01) : 1 - 13
  • [2] Gene localization in a Chinese family with autosomal dominant non-syndromic deafness
    Jiang, Lu
    Liu, Yalan
    Feng, Yong
    Hu, Zhengmao
    Mei, Lingyun
    Long, Liwei
    Chen, Hongsheng
    Xue, Jingjie
    Xia, Kun
    He, Chufeng
    ACTA OTO-LARYNGOLOGICA, 2011, 131 (10) : 1061 - 1068
  • [3] Autosomal dominant non-syndromic deafness caused by a mutation in the myosin VIIA gene
    Liu, XZ
    Walsh, J
    Tamagawa, Y
    Kitamura, K
    Nishizawa, M
    Steel, KP
    Brown, SDM
    NATURE GENETICS, 1997, 17 (03) : 268 - 269
  • [4] Autosomal dominant non-syndromic deafness caused by a mutation in the myosin VIIA gene
    Xue-Zhong Liu
    James Walsh
    Yuya Tamagawa
    Ken Kitamura
    Masatoyo Nishizawa
    Karen P. Steel
    Steve D.M. Brown
    Nature Genetics, 1997, 17 : 268 - 269
  • [5] Gene Screening for Non-Syndromic Deafness in Hainanese Patients
    Fu, Yifei
    Zhao, Zhibin
    Zheng, Jing
    Zhu, Yuanping
    Sun, Liang
    JOURNAL OF INTERNATIONAL ADVANCED OTOLOGY, 2023, 19 (04): : 283 - 287
  • [6] A GENE RESPONSIBLE FOR A DOMINANT FORM OF NEUROSENSORY NON-SYNDROMIC DEAFNESS MAPS TO THE NSRD1 RECESSIVE DEAFNESS GENE INTERVAL
    CHAIB, H
    LINAGRANADE, G
    GUILFORD, P
    PLAUCHU, H
    LEVILLIERS, J
    MORGON, A
    PETIT, C
    HUMAN MOLECULAR GENETICS, 1994, 3 (12) : 2219 - 2222
  • [7] Neurootological findings of autosomal dominant non-syndromic deafness caused by a mutation in the myosin VIIBA gene
    Kitamura, K
    Tamagawa, Y
    Kakoi, H
    EQUILIBRIUM RESEARCH, CLINICAL EQUILIBRIOMETRY AND MODERN TREATMENT, 2000, 1201 : 674 - 674
  • [8] A new locus for non-syndromic autosomal dominant congenital cataract on chromosome 19.
    Kumar, V
    Singh, D
    Hennies, HC
    Sperling, K
    Singh, JR
    AMERICAN JOURNAL OF HUMAN GENETICS, 2003, 73 (05) : 477 - 477
  • [9] Non-syndromic hearing impairment: gene linkage and cloning
    Smith, RJH
    Van Camp, G
    INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 1999, 49 : S159 - S163
  • [10] Analysis of TRIOBP gene in non-syndromic deafness: A case report
    Zhou, Hong
    Guo, Gang
    Gao, Jianjun
    Duan, Hong
    MEDICINE, 2024, 103 (45)
12345