Intracranial Metastasis in a Patient with Hepatocellular Carcinoma and Gastric Cancer

被引：3

作者：

Tawada, Akinobu ^{[1
]}

Chiba, Tetsuhiro ^{[1
]}

Ooka, Yoshihiko ^{[1
]}

Yokota, Hajime ^{[2
]}

Kanogawa, Naoya ^{[1
]}

Motoyama, Tenyu ^{[1
]}

Saito, Tomoko ^{[1
]}

Ogasawara, Sadahisa ^{[1
]}

Suzuki, Eiichiro ^{[1
]}

Hanari, Naoyuki ^{[3
]}

Matsubara, Hisahiro ^{[3
]}

Saeki, Naokatsu ^{[4
]}

Kambe, Michiyo ^{[5
]}

Kishimoto, Takashi ^{[6
]}

Nakatani, Yukio ^{[5
]}

Yokosuka, Osamu ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Med, Dept Gastroenterol & Nephrol, Chiba, Japan

[2] Chiba Univ, Grad Sch Med, Dept Radiol, Chiba, Japan

[3] Chiba Univ, Grad Sch Med, Dept Frontier Surg, Chiba, Japan

[4] Chiba Univ, Grad Sch Med, Dept Neurol Surg, Chiba, Japan

[5] Chiba Univ, Grad Sch Med, Dept Diagnost Pathol, Chiba, Japan

[6] Chiba Univ, Grad Sch Med, Dept Mol Pathol, Chiba, Japan

来源：

CASE REPORTS IN ONCOLOGY | 2014年 / 7卷 / 01期

关键词：

Multiple primary malignancy; Hepatocellular carcinoma; Gastric cancer; Double cancer; Intracranial metastasis; Surgical resection;

D O I：

10.1159/000360982

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A 76-year-old man was referred to our hospital with visual disturbance, weakness of the left upper and lower limbs, and gait disturbance. He had previously received transarterial chemoembolization for hepatocellular carcinoma (HCC) 3 and 10 years ago. When he had received radiofrequency ablation for HCC recurrence 2 years ago, total gastrectomy was also performed for his gastric cancer. Subsequently, sorafenib had been administrated for concomitant lung metastatic tumors. On admission, MRI revealed an intra-axial tumor with perifocal edema. The level of carcinoembryonic antigen, but not alpha-fetoprotein, markedly increased. The tumor was successfully removed by craniotomy and pathological examination revealed that it was composed of adenocarcinoma, which was consistent with the primary gastric cancer. After surgery, his neurological disturbances rapidly resolved. Additional gamma-knife treatment was also performed for another small brain metastasis detected after craniotomy. Subsequently, sorafenib administration was discontinued and S-1 was administered postoperatively. Successful treatment of intracranial metastasis of gastric cancer is important and meaningful, even in patients with multiple primary malignancies. (C) 2014 S. Karger AG, Basel

引用

页码：199 / 203

页数：5

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