Risk management of risk management: Combining proton pump inhibitors with low-dose aspirin

被引：2

作者：

Vonkeman, Harald ^{[1
]}

Meek, Inger

van de Laar, Mart

机构：

[1] Med Spectrum Twente, Arthrit Ctr Twente, Dept Rheumatol & Clin Immunol, Arenspl 1, NL-7511 JX Enschede, Netherlands

来源：

DRUG HEALTHCARE AND PATIENT SAFETY | 2010年 / 2卷

关键词：

low-dose aspirin; gastrointestinal ulcers; Helicobacter pylori; proton-pump inhibitors; H-2-receptor antagonists; clopidogrel;

D O I：

10.2147/DHPS.S7206

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Low-dose aspirin is widely used in the primary and secondary prevention of cardiovascular events, but is associated with a range of upper gastrointestinal side effects. In this review, we summarize the rationale for low-dose aspirin therapy, quantify the risk for upper gastrointestinal side effects, identify the risk factors involved, and provide an overview of preventive strategies, thereby focusing on the rationale and clinical utility of combining proton-pump inhibitors with low-dose aspirin.

引用

页码：191 / 204

页数：14

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