MUSCARINIC INVOLVEMENT IN VASCULAR AND ADRENAL-MEDULLARY RESPONSES TO SPLANCHNIC NERVE-STIMULATION IN CONSCIOUS CALVES

被引：2

作者：

JONES, CT ^{[1
]}

EDWARDS, AV ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,PHYSIOL LAB,CAMBRIDGE CB2 3EG,ENGLAND

来源：

EXPERIENTIA | 1994年 / 50卷 / 10期

关键词：

SYMPATHETIC; ADRENAL MEDULLA; NICOTINIC; MUSCARINIC; CATECHOLAMINES; ENKEPHALINS; CORTICOTROPIN RELEASING FACTOR (CRF);

D O I：

10.1007/BF01923481

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Stimulation of the peripheral end of the right splanchnic nerve (4 Hz for 10 min) in the presence of hexamethonium caused a small but significant rise in mean aortic blood pressure which was subsequently abolished by atropine. There were also small but significant increases in the outputs of catecholamines, [Met(5)]-enkephalins and corticotrophin releasing factor (CRF) from the right adrenal gland. The catecholamine response was roughly halved after atropine while the outputs of enkephalins and CRF were unaffected. It is concluded that splanchnic sympathetic postganglionic neurones supplying the vasculature are completely blocked by cholinergic blockade whereas adrenal medullary responses persist in an attenuated form.

引用

页码：931 / 935

页数：5

共 22 条

[1]

ARKINSTALL SJ, 1985, J REPROD FERTIL, V73, P547, DOI 10.1530/jrf.0.0730547

[2] ADRENAL-CORTICAL RESPONSES TO VASOACTIVE-INTESTINAL-PEPTIDE IN CONSCIOUS HYPOPHYSECTOMIZED CALVES [J].

BLOOM, SR ;

EDWARDS, AV ;

JONES, CT .

JOURNAL OF PHYSIOLOGY-LONDON, 1987, 391 :441-450

[3] THE ADRENAL CONTRIBUTION TO THE NEURO-ENDOCRINE RESPONSES TO SPLANCHNIC NERVE-STIMULATION IN CONSCIOUS CALVES [J].

BLOOM, SR ;

EDWARDS, AV ;

JONES, CT .

JOURNAL OF PHYSIOLOGY-LONDON, 1988, 397 :513-526

[4] DEVELOPMENT OF ADRENAL MEDULLA OF FOETAL AND NEW-BORN CALF [J].

COMLINE, RS ;

SILVER, M .

JOURNAL OF PHYSIOLOGY-LONDON, 1966, 183 (02) :305-&

[5] RELEASE OF ADRENALINE AND NORADRENALINE FROM ADRENAL GLANDS OF FOETAL SHEEP [J].

COMLINE, RS ;

SILVER, M .

JOURNAL OF PHYSIOLOGY-LONDON, 1961, 156 (03) :424-&

[6]

EDWARDS AV, 1986, J PHYSIOL-LONDON, V379, P1, DOI 10.1113/jphysiol.1986.sp016237

[7] ADRENAL-CORTICAL AND MEDULLARY RESPONSES TO ACETYLCHOLINE AND VASOACTIVE-INTESTINAL-PEPTIDE IN CONSCIOUS CALVES [J].

EDWARDS, AV ;

JONES, CT .

JOURNAL OF PHYSIOLOGY-LONDON, 1993, 468 :515-527

[8] SECRETION OF CORTICOTROPIN RELEASING-FACTOR FROM THE ADRENAL DURING SPLANCHNIC NERVE-STIMULATION IN CONSCIOUS CALVES [J].

EDWARDS, AV ;

JONES, CT .

JOURNAL OF PHYSIOLOGY-LONDON, 1988, 400 :89-100

[9] EFFECTS OF INFUSIONS OF SYNTHETIC ADRENOCORTICOTROPIN IN CONSCIOUS CALF [J].

EDWARDS, AV ;

HARDY, RN ;

MALINOWSKA, KW .

JOURNAL OF PHYSIOLOGY-LONDON, 1974, 239 (03) :477-498

[10] THE EFFECT OF SPLANCHNIC NERVE-STIMULATION ON ADRENOCORTICAL ACTIVITY IN CONSCIOUS CALVES [J].

EDWARDS, AV ;

JONES, CT .

JOURNAL OF PHYSIOLOGY-LONDON, 1987, 382 :385-396

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