A NEW CHEMICAL SYNTHESIS OF ALPHA,ALPHA-TREHALOSE

被引：24

作者：

CHITTEND.GJ

机构：

[1] Microbiological Chemistry Research Laboratory, Department of Organic Chemistry, University of Newcastle upon Tyne Great Britain

来源：

CARBOHYDRATE RESEARCH | 1969年 / 9卷 / 03期

关键词：

D O I：

10.1016/S0008-6215(00)80170-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

2,3,4,6-Tetra-O-benzyl-d-glucopyranose has been treated with 2 equivalents of the corresponding glycosyl chloride under modified Koenigs-Knorr reaction conditions. Hydrogenolysis of the protecting groups of the syrupy product, followed by chromatography on Dowex-1 (HO-) resin gave α,α-trehalose (α-d-glucopyranosyl α-d-glucopyranoside) and α,β-trehalose (α-d-glucopyranosyl β-d-glucopyranoside) in yields of 18 and 2%, respectively. © 1969.

引用

页码：323 / &

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