INHIBITION OF TOLBUTAMIDE METABOLISM BY SUBSTITUTED IMIDAZOLE DRUGS INVIVO - EVIDENCE FOR A STRUCTURE-ACTIVITY RELATIONSHIP

被引：27
作者：
BACK, DJ
TJIA, JF
机构：
来源：
BRITISH JOURNAL OF PHARMACOLOGY | 1985年 / 85卷 / 01期
关键词：
D O I：
10.1111/j.1476-5381.1985.tb08838.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：121 / 126
页数：6
相关论文
共 23 条
[1]   TOLBUTAMIDE AS A MODEL-DRUG FOR THE STUDY OF ENZYME-INDUCTION AND ENZYME-INHIBITION IN THE RAT [J].
BACK, DJ ;
SUTCLIFFE, F ;
TJIA, JF .
BRITISH JOURNAL OF PHARMACOLOGY, 1984, 81 (03) :557-562
[2]  
DREW R, 1983, 2 WORLD C CLIN PHARM
[3]   EFFECT OF CIMETIDINE ON ACETAMINOPHEN PHARMACOKINETICS IN RATS [J].
GALINSKY, RE ;
LEVY, G .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1982, 10 (04) :301-306
[4]  
KAHL R, 1980, DRUG METAB DISPOS, V8, P191
[5]  
LEIBMAN KC, 1973, DRUG METAB DISPOS, V1, P775
[6]   INHIBITORS OF HEPATIC MIXED-FUNCTION OXIDASES .5. INHIBITION OF AMINOPYRINE N-DEMETHYLATION AND ENHANCEMENT OF ANILINE HYDROXYLATION BY BENZOXAZOLE DERIVATIVES [J].
LITTLE, PJ ;
RYAN, AJ .
BIOCHEMICAL PHARMACOLOGY, 1982, 31 (09) :1795-1798
[7]  
MAILMAN RB, 1974, DRUG METAB DISPOS, V2, P301
[8]  
NIEMEGEERS CJE, 1981, ARCH INT PHARMACODYN, V251, P27
[9]  
OREILLY RA, 1976, NEW ENGL J MED, V295, P354, DOI 10.1056/NEJM197608122950702
[10]   EFFECTS OF 1-ALKYLIMIDAZOLES ON HEPATIC DRUG-METABOLIZING ENZYME-ACTIVITY [J].
PALMER, ED ;
CAWTHORNE, MA .
XENOBIOTICA, 1974, 4 (04) :209-217
123