LIPASE CATALYSIS IN ORGANIC-SOLVENTS - IN SEARCH OF PRACTICAL DERIVATIZING AGENTS FOR THE KINETIC RESOLUTION OF ALCOHOLS

被引：8
作者：
BEVINAKATTI, HS
NEWADKAR, RV
机构：
[1] Alchemie Research Centre, ICI India Ltd Site, Thane, 400 601, Thane- Belapur Road
来源：
TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 05期
关键词：
D O I：
10.1016/S0957-4166(00)80114-7
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
2-Phenyloxazolin-5-one (2) acts as a 'derivatizing agent' in the lipase catalyzed kinetic resolution of N-ethoxycarbonyl-2-amino-1-butanol (1) inorganic solvents. Unique structural alteration possible due to condensation with 2 gives enough scope for the separation of product and substrate isomers without using column chromatography.
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页码：773 / 776
页数：4
相关论文
共 21 条
[1]   LIPASE CATALYSIS IN ORGANIC-SOLVENTS - APPLICATION TO THE SYNTHESIS OF (R)-ATENOLOL AND (S)-ATENOLOL [J].
BEVINAKATTI, HS ;
BANERJI, AA .
JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (22) :6003-6005
[2]   LIPASE CATALYSIS IN ORGANIC-SOLVENTS TRANS-ESTERIFICATION OF ORTHO-FORMYL ESTERS OF SECONDARY ALCOHOLS [J].
BEVINAKATTI, HS ;
NEWADKAR, RV .
BIOTECHNOLOGY LETTERS, 1989, 11 (11) :785-788
[3]   ENZYMATIC-SYNTHESIS OF OPTICALLY-ACTIVE AMINO-ACIDS - EFFECT OF SOLVENT ON THE ENANTIOSELECTIVITY OF LIPASE-CATALYZED RING-OPENING OF OXAZOLIN-5-ONES [J].
BEVINAKATTI, HS ;
BANERJI, AA ;
NEWADKAR, RV ;
MOKASHI, AA .
TETRAHEDRON-ASYMMETRY, 1992, 3 (12) :1505-1508
[4]   LIPASE-CATALYZED ENANTIOSELECTIVE RING-OPENING OF OXAZOL-5(4H)-ONES COUPLED WITH PARTIAL INSITU RACEMIZATION OF THE LESS REACTIVE ISOMER [J].
BEVINAKATTI, HS ;
NEWADKAR, RV ;
BANERJI, AA .
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1990, (16) :1091-1092
[5]   RESOLUTION OF SECONDARY ALCOHOLS USING LIPASE IN DIISOPROPYL ETHER [J].
BEVINAKATTI, HS ;
BANERJI, AA ;
NEWADKAR, RV .
JOURNAL OF ORGANIC CHEMISTRY, 1989, 54 (10) :2453-2455
[6]   PRACTICAL CHEMOENZYMATIC SYNTHESIS OF BOTH ENANTIOMERS OF PROPRANOLOL [J].
BEVINAKATTI, HS ;
BANERJI, AA .
JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (18) :5372-5375
[7]   LIPASE-CATALYZED KINETIC RESOLUTION OF N,O-DIACETYL-2-AMINO-1-BUTANOL IN DIISOPROPYL ETHER [J].
BEVINAKATTI, HS ;
NEWADKAR, RV .
TETRAHEDRON-ASYMMETRY, 1990, 1 (09) :583-586
[8]  
BEVINAKATTI HS, 1990, Patent No. 957
[9]  
BEVINAKATTI HS, 1991, J ORG CHEM, V56, P7360
[10]   ANHYDRIDES AS ACYLATING AGENTS IN LIPASE-CATALYZED STEREOSELECTIVE ESTERIFICATION OF RACEMIC ALCOHOLS [J].
BIANCHI, D ;
CESTI, P ;
BATTISTEL, E .
JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (23) :5531-5534
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