ASSIGNMENT OF THE H-1 AND C-13 NMR-SPECTRA OF THE C-21 STEROIDS 12-BETA-O-ACETYLTENACIGENIN-A AND TENACIGENIN-A BY 2-DIMENSIONAL NMR TECHNIQUES AND COMPUTER MODELING

被引：19
作者：
LUO, SQ
LIN, LZ
CORDELL, GA
XUE, LA
JOHNSON, ME
机构：
[1] UNIV ILLINOIS,COLL PHARM,PROGRAM COLLABORAT RES PHARMACEUT SCI,CHICAGO,IL 60612
[2] UNIV ILLINOIS,COLL PHARM,DEPT MED CHEM & PHARMACOGNOSY,CHICAGO,IL 60612
来源：
MAGNETIC RESONANCE IN CHEMISTRY | 1993年 / 31卷 / 03期
关键词：
2D NMR (DQF-COSY; ROESY; HETCOR; FLOCK); CONFORMATION; C-21; STEROIDS; 12-BETA-O-ACETYLTENACIGENIN-A; TENACIGENIN-A; MARSDENIA-TENACISSIMA;
D O I：
10.1002/mrc.1260310302
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Stereochemical assignments of the C21 steroids 12-beta-O-acetyltenacigenin A and tenacigenin A were performed by use of two-dimensional phase-sensitive COSY, ROESY, H-1 and C-13 shift correlation spectroscopy (HETCOR and FLOCK), and ambiguous assignments were resolved through molecular modeling comparisons. This combination of techniques is applicable for the assignment of the highly overlapped H-1 signals of these steroids.
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页码：215 / 221
页数：7
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