IS MUSCLE THE MAJOR SITE OF INSULIN RESISTANCE IN TYPE-2 (NON-INSULIN-DEPENDENT) DIABETES-MELLITUS

被引：55
作者：
GERICH, JE [1 ]
机构：
[1] UNIV PITTSBURGH,SCH MED,CLIN RES CTR,DEPT PHYSIOL,PITTSBURGH,PA 15261
来源：
DIABETOLOGIA | 1991年 / 34卷 / 08期
关键词：
D O I：
10.1007/BF00400282
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：607 / 610
页数：4
相关论文
共 29 条
[1]   QUANTITATIVELY MINOR ROLE OF CARBOHYDRATE IN OXIDATIVE METABOLISM BY SKELETAL MUSCLE IN INTACT MAN IN THE BASAL STATE - MEASUREMENTS OF OXYGEN AND GLUCOSE UPTAKE AND CARBON DIOXIDE AND LACTATE PRODUCTION IN THE FOREARM [J].
ANDRES, R ;
CADER, G ;
ZIERLER, KL .
JOURNAL OF CLINICAL INVESTIGATION, 1956, 35 (06) :671-682
[2]   RATES AND TISSUE SITES OF NON-INSULIN-MEDIATED AND INSULIN-MEDIATED GLUCOSE-UPTAKE IN HUMANS [J].
BARON, AD ;
BRECHTEL, G ;
WALLACE, P ;
EDELMAN, SV .
AMERICAN JOURNAL OF PHYSIOLOGY, 1988, 255 (06) :E769-E774
[3]   INSULIN RESISTANCE IN SKELETAL-MUSCLES OF PATIENTS WITH DIABETES-MELLITUS [J].
BECKNIELSEN, H .
DIABETES-METABOLISM REVIEWS, 1989, 5 (06) :487-493
[4]   RELATIONSHIPS BETWEEN INSULIN-SECRETION, INSULIN ACTION, AND FASTING PLASMA-GLUCOSE CONCENTRATION IN NONDIABETIC AND NONINSULIN-DEPENDENT DIABETIC SUBJECTS [J].
BOGARDUS, C ;
LILLIOJA, S ;
HOWARD, BV ;
REAVEN, G ;
MOTT, D .
JOURNAL OF CLINICAL INVESTIGATION, 1984, 74 (04) :1238-1246
[5]   OBESITY AND INSULIN RESISTANCE IN HUMANS - A DOSE-RESPONSE STUDY [J].
BONADONNA, RC ;
GROOP, L ;
KRAEMER, N ;
FERRANNINI, E ;
DELPRATO, S ;
DEFRONZO, RA .
METABOLISM-CLINICAL AND EXPERIMENTAL, 1990, 39 (05) :452-459
[6]   QUANTIFICATION OF THE RELATIVE IMPAIRMENT IN ACTIONS OF INSULIN ON HEPATIC GLUCOSE-PRODUCTION AND PERIPHERAL GLUCOSE-UPTAKE IN NON-INSULIN-DEPENDENT DIABETES-MELLITUS [J].
CAMPBELL, PJ ;
MANDARINO, LJ ;
GERICH, JE .
METABOLISM-CLINICAL AND EXPERIMENTAL, 1988, 37 (01) :15-21
[7]   DIRECT EVIDENCE FOR A STIMULATORY EFFECT OF HYPERGLYCEMIA PER-SE ON PERIPHERAL GLUCOSE DISPOSAL IN TYPE-II DIABETES [J].
CAPALDO, B ;
SANTORO, D ;
RICCARDI, G ;
PERROTTI, N ;
SACCA, L .
JOURNAL OF CLINICAL INVESTIGATION, 1986, 77 (04) :1285-1290
[8]   RELATIONSHIP BETWEEN PLASMA-GLUCOSE AND INSULIN CONCENTRATION, GLUCOSE-PRODUCTION, AND GLUCOSE DISPOSAL IN NORMAL SUBJECTS AND PATIENTS WITH NON-INSULIN-DEPENDENT DIABETES [J].
CHEN, YDI ;
JENG, CY ;
HOLLENBECK, CB ;
WU, MS ;
REAVEN, GM .
JOURNAL OF CLINICAL INVESTIGATION, 1988, 82 (01) :21-25
[9]   EFFECTS OF INSULIN ON PERIPHERAL AND SPLANCHNIC GLUCOSE-METABOLISM IN NONINSULIN-DEPENDENT (TYPE-II) DIABETES-MELLITUS [J].
DEFRONZO, RA ;
GUNNARSSON, R ;
BJORKMAN, O ;
OLSSON, M ;
WAHREN, J .
JOURNAL OF CLINICAL INVESTIGATION, 1985, 76 (01) :149-155
[10]   FASTING HYPERGLYCEMIA IN NON-INSULIN-DEPENDENT DIABETES-MELLITUS - CONTRIBUTIONS OF EXCESSIVE HEPATIC GLUCOSE-PRODUCTION AND IMPAIRED TISSUE GLUCOSE-UPTAKE [J].
DEFRONZO, RA ;
FERRANNINI, E ;
SIMONSON, DC .
METABOLISM-CLINICAL AND EXPERIMENTAL, 1989, 38 (04) :387-395
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