SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 3-VINYLTHIOMETHYLCEPHEM AND 3-VINYLTHIOMETHYLCEPHEM DERIVATIVES

被引：8
作者：
NISHIMURA, S
YASUDA, N
SASAKI, H
KAWABATA, K
SAKANE, K
TAKAYA, T
机构：
[1] New Drug Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Yodogawa-ku, Osaka 532
来源：
JOURNAL OF ANTIBIOTICS | 1990年 / 43卷 / 09期
关键词：
D O I：
10.7164/antibiotics.43.1160
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The synthesis and biological properties of some 3-vinylthio- and 3-vinylthiomethylcephem derivatives are described. Both series possess potent antibacterial activity. Among them, 3-[(Z)-2-cyanovinylthiomethyl]cephem derivative was found to have an expanded antibacterial spectrum. © 1990, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.
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页码：1160 / 1168
页数：9
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