MOSSBAUER SPECTROSCOPIC STUDIES ON THE BIS(HISTIDINE) ADDUCTS OF (PROTOPORPHYRINATO-IX)IRON(II)

被引：6

作者：

MEDHI, OK ^{[1
]}

SILVER, J ^{[1
]}

机构：

[1] UNIV ESSEX,DEPT CHEM & BIOL CHEM,WIVENHOE PK,COLCHESTER CO4 3SQ,ESSEX,ENGLAND

来源：

INORGANICA CHIMICA ACTA | 1990年 / 168卷 / 02期

关键词：

D O I：

10.1016/S0020-1693(00)80954-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Mössbauer spectra in frozen aqueous ethanolic solution of complexes of the type [(PPIX)Fe(II)-(HisR)2] are reported where HisR = histidine, N-α-acetyl histidine, pilocarpate or histamine. At alkaline pH 12.0, the complexes are found to be monomeric and low spin with quadrupole splittings (ΔEQ) similar to that of reduced cytochrome b5. The ΔEQ values are typical of bis(imidazole) coordination to (protoporphyrinato IX)iron(II) (ΔEQ = 0.9-1.04 mm s-1). The results indicate that hydrogen bonding to the NH of the coordinated imidazole considerably decreases the ΔEQ values. © 1990.

引用

页码：271 / 274

页数：4

共 17 条

[1] MOSSBAUER SPECTROSCOPIC EVIDENCE FOR LOW-SPIN IRON IN DEHYDRATED METMYOGLOBIN [J].

CAUGHEY, WS ;

FUJIMOTO, WY ;

BEARDEN, AJ ;

MOSS, TH .

BIOCHEMISTRY, 1966, 5 (04) :1255-&

[2] SYNTHETIC MODELS FOR OXYGEN-BINDING HEMOPROTEINS [J].

COLLMAN, JP .

ACCOUNTS OF CHEMICAL RESEARCH, 1977, 10 (07) :265-272

[3]

CONNEY AH, 1967, PHARMACOL REV, V19, P317

[4]

Dolphin D., 1979, PORPHYRINS, V1

[5]

HOARD JL, 1975, PORPHYRINS METALLOPO, pCH8

[6]

JONES RD, 1977, CHEM REV, V10, P265

[7] ON THE PROPERTIES AND NATURE OF DIHYDROXYL-HAEM [J].

KEILIN, J .

BIOCHEMICAL JOURNAL, 1949, 45 (04) :448-455

[8] THE MOSSBAUER SPECTRUM OF AN INTERMEDIATE SPIN (S = 1) 4-COORDINATED (PROTOPORPHYRINATO-IX)IRON(II) COMPLEX IN A FROZEN AQUEOUS-SOLUTION OF CETYLTRIMETHYLAMMONIUM BROMIDE [J].

MEDHI, OK ;

SILVER, J .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1989, (17) :1199-1200

[9] NATURE OF HEME-HEME INTERACTION [J].

PERUTZ, MF .

NATURE, 1972, 237 (5357) :495-&

[10]

REID CA, 1980, MET IONS BIOL SYST, V7, P73

← 1 2 →