POSITIVELY CHARGED RESIDUES ARE IMPORTANT DETERMINANTS OF MEMBRANE-PROTEIN TOPOLOGY

被引：119
作者：
DALBEY, RE
机构：
[1] Department of Chemistry, The Ohio State University, Columbus
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 1990年 / 15卷 / 07期
基金：
美国国家科学基金会;
关键词：
D O I：
10.1016/0968-0004(90)90047-F
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Membrane proteins are found in a variety of conformations, with each protein spanning the membrane a set number of times and adopting a particular orientation. Positively charged residues, often located near the boundaries of transmembrane segments, appear to be involved in specifying the topology of membrane proteins. © 1990.
引用
收藏
页码：253 / 257
页数：5
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