AN OPERATIONAL MODEL OF PHARMACOLOGICAL AGONISM - THE EFFECT OF E/[A] CURVE SHAPE ON AGONIST DISSOCIATION-CONSTANT ESTIMATION

被引：229
作者：
BLACK, JW
LEFF, P
SHANKLEY, NP
WOOD, J
机构：
[1] WELLCOME RES LABS,LANGLEY COURT,BECKENHAM BR3 3BS,KENT,ENGLAND
[2] UNIV LONDON KINGS COLL HOSP,RAYNE INST,LONDON SE5 8RX,ENGLAND
来源：
BRITISH JOURNAL OF PHARMACOLOGY | 1985年 / 84卷 / 02期
关键词：
D O I：
10.1111/j.1476-5381.1985.tb12941.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：561 / 571
页数：11
相关论文
共 21 条
  • [1] RECEPTORS FOR 5-HYDROXYTRYPTAMINE AND NORADRENALINE IN RABBIT ISOLATED EAR ARTERY AND AORTA
    APPERLEY, E
    HUMPHREY, PPA
    LEVY, GP
    [J]. BRITISH JOURNAL OF PHARMACOLOGY, 1976, 58 (02) : 211 - 221
  • [2] AFFINITY AND EFFICACY OF ONIUM SALTS ON FROG RECTUS ABDOMINIS
    BARLOW, RB
    SCOTT, NC
    STEPHENSON, RP
    [J]. BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1967, 31 (01): : 188 - +
  • [3] BESSE JC, 1976, J PHARMACOL EXP THER, V197, P66
  • [4] OPERATIONAL MODELS OF PHARMACOLOGICAL AGONISM
    BLACK, JW
    LEFF, P
    [J]. PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1983, 220 (1219): : 141 - 162
  • [5] COLQUHOUN D, 1973, DRUG RECEPTORS, P149, DOI DOI 10.1007/978-1-349-00910-7_11
  • [6] DIXON WJ, 1981, BMDP STATISTICAL SOF
  • [7] FOZARD JR, 1976, BRIT J PHARMACOL, V57, P155
  • [8] Furchgott RF, 1966, ADV DRUG RES, P21
  • [9] AN ACTION OF 5-HYDROXYTRYPTAMINE ON ADRENALINE RECEPTORS
    INNES, IR
    [J]. BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1962, 19 (03): : 427 - &
  • [10] JENKINSON DH, 1979, 6 P INT S MED CHEM, P373
123