Discrepancies between Antimullerian Hormone and Follicle Stimulating Hormone in Assisted Reproduction

被引：11

作者：

Hussain, Munawar ^{[1
]}

Cahill, David ^{[2
]}

Akande, Valentine ^{[3
,4
]}

Gordon, Uma ^{[3
,4
]}

机构：

[1] St Michaels Hosp, Univ Hosp Bristol NHS Fdn Trust, Southwell St Bristol, Bristol BS2 8EG, Avon, England

[2] Univ Bristol, St Michaels Hosp, Bristol BS2 8EG, Avon, England

[3] Southmead Hosp, North Bristol NHS Trust, Bristol BS10 5NB, Avon, England

[4] Bristol Ctr Reprod Med Bristol, Bristol BS10 5NB, Avon, England

来源：

OBSTETRICS AND GYNECOLOGY INTERNATIONAL | 2013年 / 2013卷

关键词：

D O I：

10.1155/2013/383278

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Data from 107 women undergoing their first IVF/ICSI were analyzed. Relationships between antimullerian hormone (AMH) and follicle stimulating hormone (FSH) were analyzed after dividing patients into four groups according to AMH/FSH levels. Concordance was noted in 57% of women (both AMH/FSHeither normal or abnormal) while 43% of women had discordant values (AMH/FSH one hormone normal and the other abnormal). Group 1 (AMH and FSH in normal range) and group 2 (normal AMH and high FSH) were younger compared to group 3 (low AMH and normal FSH) and group 4 (both AMH/FSH abnormal). Group 1 showing the best oocyte yield was compared to the remaining three groups. Groups 3 and 4 required higher dose of gonadotrophins for controlled ovarian hyperstimulation showing their low ovarian reserve. There was no difference in cycle cancellation, clinical pregnancy, and live birth/ongoing pregnancy rate in all groups. These tests are useful to predict ovarian response but whether AMH is a substantially better predictor is not yet established.

引用

页数：6

共 42 条

[41] Statistically significant changes of antimuillerian hormone and inhibin levels during the physiologic menstrual cycle in reproductive age women [J].