DYNAMICS OF 5-HYDROXYTRYPTAMINE RELEASED FROM DOPAMINE NEURONS IN THE CAUDATE-PUTAMEN OF THE RAT

被引：35

作者：

JACKSON, BP ^{[1
]}

WIGHTMAN, RM ^{[1
]}

机构：

[1] UNIV N CAROLINA, DEPT CHEM, CHAPEL HILL, NC 27599 USA

来源：

BRAIN RESEARCH | 1995年 / 674卷 / 01期

关键词：

CYCLIC VOLTAMMETRY; IN VIVO; 5-HYDROXYTRYPTAMINE; DOPAMINE; UPTAKE TRANSPORTER; FLUOXETINE; NOMIFENSINE;

D O I：

10.1016/0006-8993(95)00019-M

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Fast-scan cyclic voltammetry has been used for the detection of 5-hydroxytryptamine (5-HT) in vivo. The applied potential waveform was previously optimized to maximize response times to concentration changes. This technique has been used to reinvestigate 5-HT release from striatal dopaminergic terminals after pharmacological pretreatment as reported by Stamford et al. [13]. Our results concur with those set forth by Stamford and further show that the dopamine transporter is responsible for 5-HT uptake in this experiment.

引用

页码：163 / 166

页数：4

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