Adverse effects associated with the use of anabolic agents in athletes: systematic review

被引:0
作者
Urios Lopez, Ricardo [1 ]
Sanz-Valero, Javier [1 ,2 ]
机构
[1] Univ Miguel Hernandez, Fac Farm, Sant Joan dAlacant, Spain
[2] Fdn Fomento Invest Sanitaria & Biomed Comunidad I, Alicante, Spain
关键词
Anabolic Agents; Adverse Effects; Sports; Systematic Review;
D O I
10.4321/S2340-98942018000100005
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Objective: Review the scientific documentation on the adverse effects of anabolic agents in adults who practice sports. Method: Descriptive cross-sectional study and critical analysis of the works recovered through systematic review. The data were obtained from direct consultation and access, via the Internet, to the following bibliographic databases in the field of health sciences: MEDLINE (via PubMed), The Cochrane Library, Scopus, Cumulative Index to Nursing and Allied Health Literature (CINHAL), Web of Science y PsycINFO until October 2017. The use of Descriptors was considered appropriate ''Sports'', ''Anabolic Agents/Adverse effects'', using the filters: ''Clinical Trial'', ''Comparative Study'', ''Humans'' y ''Adult: 19+years''. Results: Of the 108 recovered references, after applying the inclusion and exclusion criteria, 15 articles were selected for review. One job was found in the bibliographic listings. By evaluating the quality of selected articles for review using the CONSORT questionnaire, scores ranged from 11,5 to 15,5 on a maximum score of 25. Conclusions: The revised work presented a higher obsolescence than expected in the area of health sciences. The articles were written preferably in English. It was observed, that the AAS had adverse effects, especially at the cardiovascular, behavioral level and appearance of side effects associated with the consumption of anabolic agents. Although there are discrepancies between the magnitude of them at the cardiovascular level and their potential damage.
引用
收藏
页码:45 / 55
页数:11
相关论文
共 42 条
[1]   REDUCED HIGH-DENSITY LIPOPROTEIN-CHOLESTEROL IN POWER ATHLETES - USE OF MALE SEX-HORMONE DERIVATES, AN ATHEROGENIC FACTOR [J].
ALEN, M ;
RAHKILA, P .
INTERNATIONAL JOURNAL OF SPORTS MEDICINE, 1984, 5 (06) :341-342
[2]   Management of gynecomastia due to use of anabolic steroids in bodybuilders [J].
Babigian, A ;
Silverman, RT .
PLASTIC AND RECONSTRUCTIVE SURGERY, 2001, 107 (01) :240-242
[3]   Long-Term Anabolic-Androgenic Steroid Use Is Associated With Left Ventricular Dysfunction [J].
Baggish, Aaron L. ;
Weiner, Rory B. ;
Kanayama, Gen ;
Hudson, James I. ;
Picard, Michael H. ;
Hutter, Adolph M., Jr. ;
Pope, Harrison G., Jr. .
CIRCULATION-HEART FAILURE, 2010, 3 (04) :472-U15
[4]   ASSESSMENT OF ATTENTIONAL BIAS AND MOOD IN USERS AND NONUSERS OF ANABOLIC-ANDROGENIC STEROIDS [J].
BOND, AJ ;
CHOI, PYL ;
POPE, HG .
DRUG AND ALCOHOL DEPENDENCE, 1995, 37 (03) :241-245
[5]   Recruitment to doping and help-seeking behavior of eight female AAS users [J].
Borjesson, Annica ;
Garevik, Nina ;
Dahl, Marja-Liisa ;
Rane, Anders ;
Ekstrom, Lena .
SUBSTANCE ABUSE TREATMENT PREVENTION AND POLICY, 2016, 11
[6]   Human Growth Hormone Abuse in Male Weightlifters [J].
Brennan, Brian P. ;
Kanayama, Gen ;
Hudson, James I. ;
Pope, Harrison G., Jr. .
AMERICAN JOURNAL ON ADDICTIONS, 2011, 20 (01) :9-13
[7]  
BRUNO M, 1990, Clinica Terapeutica, V135, P159
[8]   The effects of anabolic-androgenic steroids upon resting and peak exercise left ventricular heart wall motion kinetics in male strength and power athletes [J].
Climstein, M ;
O'Shea, P ;
Adams, KJ ;
DeBeliso, M .
JOURNAL OF SCIENCE AND MEDICINE IN SPORT, 2003, 6 (04) :387-397
[9]   CONSORT 2010 Declaration: Updated guideline for reporting parallel group randomised trials [J].
Cobos-Carbo, Albert ;
Augustovski, Federico .
MEDICINA CLINICA, 2011, 137 (05) :213-215
[10]   Left ventricular early myocardial dysfunction after chronic misuse of anabolic androgenic steroids:: a Doppler myocardial and strain imaging analysis [J].
D'Andrea, Antonello ;
Caso, Pio ;
Salerno, Gemma ;
Scarafile, Raffaella ;
De Corato, Giuseppe ;
Mita, Claudia ;
Di Salvo, Giovanni ;
Severino, Sergio ;
Cuomo, Sergio ;
Liccardo, Biagio ;
Esposito, Nicolino ;
Calabro, Raffaele .
BRITISH JOURNAL OF SPORTS MEDICINE, 2007, 41 (03) :149-155