The Efficacy of the EMLA Analgesic Cream in Compare with Placebo in Pediatric Oncology Lumbar Puncture

被引:0
作者
Qane, M. [1 ]
Ghiliyan, R. [2 ]
Hashemi, A. [3 ]
Mirmohammadi, S. J. [4 ]
Keshavarzi, S. [3 ]
Yadegar, Y. [3 ]
Shefaie, F. [1 ]
机构
[1] Shahid Sadoughi Univ Med Sci & Hlth Serv, Yazd, Iran
[2] Shahid Sadoughi Univ Med Sci & Hlth Serv, Dept Internal Med, Yazd, Iran
[3] Shahid Sadoughi Univ Med Sci & Hlth Serv, Oncol & Genet Res Ctr, Dept Pediat Hematol Oncol, Yazd, Iran
[4] Shahid Sadoughi Univ Med Sci & Hlth Serv, Hematol Oncol & Genet Res Ctr, Dept Occupat Med, Yazd, Iran
关键词
Spinal Puncture; Pain; EMLA;
D O I
暂无
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Background The present randomized clinical trial evaluated the efficacy of a topical lidocaine-prilocaine cream (EMLA) to relief pain during spinal puncture in pediatric oncology patients. Materials and Methods Sixty patients with malignancy candidate for spinal puncture were selected for this study. The patients were randomly allocated to two groups. Group A had topical EMLA cream and group B had placebo, which they received 60 to 90 minutes before spinal puncture. Pain score was rated using the Wong-Baker Faces rating score (0: no pain to 10: worst pain). Results Pain score does not reduce significantly in the topical EMLA cream in compared with placebo (p-value=0.126). No signs of infection were noted at the spinal puncture sites 24 or 48 hours after the procedure. Conclusion Results obtained from this study represents that the EMLA cream has not more analgesic effect than placebo in reducing the pain for spinal puncture.
引用
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页码:44 / 48
页数:5
相关论文
共 16 条
[1]  
ARTS SE, 1994, PEDIATRICS, V93, P797
[2]   DEPTH AND DURATION OF SKIN ANALGESIA TO NEEDLE INSERTION AFTER TOPICAL APPLICATION OF EMLA CREAM [J].
BJERRING, P ;
ARENDTNIELSEN, L .
BRITISH JOURNAL OF ANAESTHESIA, 1990, 64 (02) :173-177
[3]   Pediatric and emergency medicine residents' attitudes and practices for analgesia and sedation during lumbar puncture in pediatric patients [J].
Breakey, Vicky R. ;
Pirie, Jonathan ;
Goldman, Ran D. .
PEDIATRICS, 2007, 119 (03) :E631-E636
[4]   EUTECTIC LIDOCAINE PRILOCAINE CREAM - A REVIEW OF THE TOPICAL ANESTHETIC ANALGESIC EFFICACY OF A EUTECTIC MIXTURE OF LOCAL-ANESTHETICS (EMLA) [J].
BUCKLEY, MM ;
BENFIELD, P .
DRUGS, 1993, 46 (01) :126-151
[5]   A clinical study to evaluate the efficacy of ELA-Max (4% liposomal lidocaine) as compared with eutectic mixture of local anesthetics cream for pain reduction of venipuncture in children [J].
Eichenfield, LF ;
Funk, A ;
Fallon-Friedlander, S ;
Cunningham, BB .
PEDIATRICS, 2002, 109 (06) :1093-1099
[6]  
ENAD D, 1995, PEDIATR RES, V37, pA204
[7]  
GAJRAJ NM, 1994, ANESTH ANALG, V78, P574
[8]  
Gimenez JCJ, 1996, ANN PHARMACOTHER, V30, P1235
[9]   An investigation of the placebo effect and age-related factors in the report of needle pain from venipuncture in children [J].
Goodenough, B ;
Kampel, L ;
Champion, GD ;
Laubreaux, L ;
Nicholas, MK ;
Ziegler, JB ;
McInerney, M .
PAIN, 1997, 72 (03) :383-391
[10]  
HALPERIN DL, 1989, PEDIATRICS, V84, P281