NEW CHOICES FOR PATIENTS NEEDING KIDNEY TRANSPLANTATION ACROSS ANTIBODY BARRIERS

被引：6

作者：

Higgins, Rob ^{[1
,2
]}

Hathaway, Mark ^{[3
]}

Lowe, David ^{[3
]}

Zehnder, Daniel ^{[1
,2
,4
]}

Krishnan, Nithya ^{[1
,2
]}

Hamer, Rizwan ^{[1
,2
,4
]}

Briggs, David ^{[3
]}

机构：

[1] Univ Hosp Coventry, Transplant Unit, Coventry, W Midlands, England

[2] Univ Hosp Warwickshire, Transplant Unit, Coventry, W Midlands, England

[3] Natl Blood Serv, Histocompatibil Lab, Birmingham, W Midlands, England

[4] Univ Warwick, Warwick Med Sch, Clin Sci Res Inst, Coventry, W Midlands, England

来源：

JOURNAL OF RENAL CARE | 2008年 / 34卷 / 02期

关键词：

ABO antibody; Antibody-incompatible transplantation; HLA antibody; Kidney transplant; Plasma exchange; Plasmapheresis;

D O I：

10.1111/j.1755-6686.2008.00025.x

中图分类号：

R47 [护理学];

学科分类号：

1011 ;

摘要：

Antibodies in the blood of a kidney transplant recipient can provide a barrier to transplantation, which is additional to the usual possibility of cellular rejection. The antibodies most frequently encountered are ABO (blood group) and human leucocyte antigen (HLA) (tissue-type) antibodies. About 250 living donor transplants each year in the United Kingdom have been stopped because of an antibody barrier. It is now possible to offer a choice of treatment modalities to these people, including exchange transplantation and antibody-incompatible transplantation. It is likely that both schemes will complement each other and both are available in the United Kingdom.

引用

页码：85 / 93

页数：9

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