Growth and acid production of the mixed culture of Streptococcus thermophilus and Lactobacillus acidophilus were investigated in milk and modified milk media as a function of the solid not fat content. The microorganisms were grown on sterilized cow's milk, cow's milk + 1% glucose and cow's milk + 6% tomato juice media, containing 8.5, 10.34 and 12.18% solid not fat (controlled by addition of skim milk powder). Fermentations were run at 45 degrees C temperature with 3% starters. Results showed that addition of 1% glucose or 6% tomato juice to the cow's milk had a slight stimulatory effect on the growth and acid production of the mixed culture. Increase of the solid not fat up to 12.18% in milk media does not affect the cell counts and acid production significantly but decreases the whey syneresis in the fermented yoghurt-like products. The sensory quality of the fermented products proved to be the best in the case of the fermentation of cow's milk with addition of 1% glucose, containing 10.34% solid not fat.