Seizures caused by pyridoxine (vitamin B6) deficiency in adults: A case report and literature review

被引:25
作者
Tong, Yisha [1 ]
机构
[1] Univ Melbourne, Austin Hosp, Vasc Surg Unit, Melbourne, Vic, Australia
关键词
Adult; literature review; pyridoxine; seizure; vitamin B6;
D O I
10.5582/irdr.2014.01005
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Pyridoxine (vitamin B6) deficiency is a recognised cause of intractable seizures in neonates. However, pyridoxine deficiency related seizures in adults were rarely reported. This article reports a case of a 79 year old lady who suffered from new-onset seizures and was successfully treated with vitamin B6. The patient had chronic renal disease and weight loss due to anepithymia following a pelvic fracture. This article also reviews literatures of seizures caused by pyridoxine deficiency in adults. Seizures caused by vitamin B6 deficiency in adults may result from dietary deficiency, liver disease, pregnancy and certain medications and can be easily treated by vitamin B6 with excellent outcome. Clinicians should consider vitamin B6 deficiency as a potential aetiology of seizures, even in patients who suffer from other underlying diseases which can cause seizures.
引用
收藏
页码:52 / 56
页数:5
相关论文
共 35 条
[1]  
Agarwal S.B.S.B., 2004, JIACM, V5, P83
[2]   ISONIAZID OVERDOSE - 4 CASE-REPORTS AND REVIEW OF THE LITERATURE [J].
ALVAREZ, FG ;
GUNTUPALLI, KK .
INTENSIVE CARE MEDICINE, 1995, 21 (08) :641-644
[3]   REVERSIBLE SEIZURES AND MENTAL STATUS CHANGES IN A DIALYSIS PATIENT ON ISONIAZID PREVENTIVE THERAPY [J].
ASNIS, DS ;
BHAT, JG ;
MELCHERT, AF .
ANNALS OF PHARMACOTHERAPY, 1993, 27 (04) :444-446
[4]   Clinical features and the management of pyridoxine-dependent and pyridoxine-responsive seizures: review of 63 North American cases submitted to a patient registry [J].
Basura, Gregory J. ;
Hagland, Shawn P. ;
Wiltse, Anna M. ;
Gospe, Sidney M., Jr. .
EUROPEAN JOURNAL OF PEDIATRICS, 2009, 168 (06) :697-704
[5]   Epidemiology of pyridoxine dependent and pyridoxine responsive seizures in the UK [J].
Baxter, P .
ARCHIVES OF DISEASE IN CHILDHOOD, 1999, 81 (05) :431-433
[6]  
BAXTER P, 2001, VITAMIN RESPONSIVE C, P109
[7]   Epidemiology of pyridoxine dependent seizures in the Netherlands [J].
Been, JV ;
Bok, LA ;
Andriessen, P ;
Renier, WO .
ARCHIVES OF DISEASE IN CHILDHOOD, 2005, 90 (12) :1293-1296
[8]  
Bender D. A., 2003, NUTR BIOCH VITAMINS, P232
[9]  
Bhagavan H. N., 1985, Vitamin B-6: its role in health and disease. Proceedings of a Conference on Vitamin B-6 Nutrition and Metabolism held at the Banff Conference Centre, Banff, Alberta, Canada, October 8-10, 1984., P401
[10]  
Bowman BA, 2006, PRESENT KNOWLEDGE NU, P273