Spontaneous and Procedural Plaque Embolisation in Native Coronary Arteries: Pathophysiology, Diagnosis, and Prevention

被引:19
作者
De Maria, Giovanni Luigi [1 ,2 ]
Patel, Niket [1 ]
Kassimis, George [1 ]
Banning, Adrian P. [1 ]
机构
[1] Oxford Univ Hosp, John Radcliffe Hosp, Oxford Heart Ctr, Headley Way, Oxford OX39DU, England
[2] Univ Cattolica Sacro Cuore, Cardiovasc Med Dept, I-00168 Rome, Italy
关键词
D O I
10.1155/2013/364247
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The detachment of atherothrombotic material from the atherosclerotic coronary plaque and downstream embolisation is an underrecognized phenomenon and it causes different degrees of impairment of the coronary microcirculation. During treatment of obstructive atherosclerotic plaque by percutaneous coronary intervention (PCI) distal embolisation (DE) is considered to be inevitable and it is associated with potential clinical and prognostic implications. This review aims to assess the main aspects of both spontaneous and procedural DE, analyze their different pathophysiology, provide specific insights on the main diagnostic tools for their identification, and finally focus on the main strategies for their treatment and prevention.
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页数:15
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