Primary Small Cell Neuroendocrine Carcinoma of the Endometrium

被引：10
作者：
Abaid, Lisa N. [1 ]
Cupp, John S. [2 ]
Brown, John V., III [1 ]
Goldstein, Bram H. [1 ]
机构：
[1] Hoag Mem Hosp, Gynecol Oncol Associates, Newport Beach, CA 92663 USA
[2] Hoag Mem Hosp, Dept Pathol, Newport Beach, CA 92663 USA
来源：
CASE REPORTS IN ONCOLOGY | 2012年 / 5卷 / 02期
关键词：
Small cell neuroendocrine carcinoma; Endometrium; Gynecologic oncology;
D O I：
10.1159/000342006
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Background: Small cell neuroendocrine carcinoma is very rarely encountered within the endometrium. Case Study: A patient underwent a hysterectomy and salpingo-oophorectomy for a suspicious gynecologic condition. Pathology revealed invasive small cell neuroendocrine carcinoma of the endometrium; the neoplasm exhibited positive immunoreactivity for synaptophysin, pancytokeratin and CD56 but was negative for CD3 and CD20. Prior to chemotherapy, a completion lymphadenectomy was indicated to determine the presence of nodal metastases. Conclusion: The prognosis of small cell neuroendocrine carcinoma of the endometrium is unfavorable but prompt detection with surgery and adjuvant therapy may confer a better clinical outcome.
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收藏
页码：439 / 443
页数：5
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