6-ARYL-4,5-DIHYDRO-3(2H)-PYRIDAZINONES - A NEW CLASS OF COMPOUNDS WITH PLATELET-AGGREGATION INHIBITING AND HYPOTENSIVE ACTIVITIES

被引：97

作者：

THYES, M ^{[1
]}

LEHMANN, HD ^{[1
]}

GRIES, J ^{[1
]}

KONIG, H ^{[1
]}

KRETZSCHMAR, R ^{[1
]}

KUNZE, J ^{[1
]}

LEBKUCHER, R ^{[1
]}

LENKE, D ^{[1
]}

机构：

[1] BASF AG,DIV PHARMACEUT,D-6700 LUDWIGSHAFEN,FED REP GER

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1983年 / 26卷 / 06期

关键词：

D O I：

10.1021/jm00360a004

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：800 / 807

页数：8

共 18 条

[1]

BACHMANN G, UNPUB

[2]

BACHMANN G, 1967, Patent No. 1507475

[3]

BORN GVR, 1963, J PHYSIOL-LONDON, V168, P178, DOI 10.1113/jphysiol.1963.sp007185

[4] 6-PHENYL-4,5-DIHYDRO-3(H-2)-PYRIDAZINONES - SERIES OF HYPOTENSIVE AGENTS [J].

CURRAN, WV ;

ROSS, A .

JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (03) :273-281

[5] AN IMPROVED SYNTHESIS OF GAMMA-(3,4-UREYLENECYCLOHEXYL)-BUTYRIC ACID [J].

ENGLISH, JP ;

CLAPP, RC ;

COLE, QP ;

KRAPCHO, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1945, 67 (12) :2263-2265

[6] ANTI-PLATELET DRUGS - CLINICAL PHARMACOLOGY AND THERAPEUTIC USE [J].

GALLUS, AS .

DRUGS, 1979, 18 (06) :439-477

[7] EFFECTS OF 6-[PARA-(4-PHENYLACETYLPIPERAZIN-1-YL)PHENYL]-4,5-DIHYDRO-3(2H)PYRIDAZINONE (CCI-17810) AND ASPIRIN ON PLATELET-AGGREGATION AND ADHESIVENESS [J].

GRIFFETT, EM ;

KINNON, SM ;

KUMAR, A ;

LECKER, D ;

SMITH, GM ;

TOMICH, EG .

BRITISH JOURNAL OF PHARMACOLOGY, 1981, 72 (04) :697-705

[8]

LEBKUCHER R, 1973, Patent No. 23049776

[9]

LEBKUCHER R, 1973, Patent No. 2150685

[10]

LEBKUCHER R, 1972, Patent No. 2123246

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