CAPILLARY ELECTROPHORETIC CHIRAL SEPARATIONS USING A SULFATED BETA-CYCLODEXTRIN CONTAINING ELECTROLYTE

被引：73

作者：

WU, WH

STALCUP, AM

机构：

[1] Department of Chemisoy, University of Hawaii at Manoa, 96822, Honolulu, Hawaii

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1995年 / 18卷 / 07期

关键词：

D O I：

10.1080/10826079508010414

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Sulfated beta-cyclodextrin (SO3-beta-CD) was utilized as a chiral additive for capillary zone electrophoresis (CZE). Chiral separations of several uhcharged enantiomers, such as phensuximide, indapamide, etc., which are difficult to separate using neutral CDs, were achieved. The effects of SO3-beta-CD concentration and the pH and ionic strength of the supporting electrolyte as well as the presence of an organic modifier, methanol, were discussed.

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页码：1289 / 1315

页数：27

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