EFFECTS OF RTC-SILICONE MAXILLOFACIAL PROSTHETIC ELASTOMERS ON CELL-CULTURES

被引：8

作者：

POLYZOIS, GL ^{[1
]}

HENSTENPETTERSEN, A ^{[1
]}

KULLMAN, A ^{[1
]}

机构：

[1] SCANDINAVIAN INST DENT MAT,NIOM,HASLUM,NORWAY

来源：

JOURNAL OF PROSTHETIC DENTISTRY | 1994年 / 71卷 / 05期

关键词：

D O I：

10.1016/0022-3913(94)90191-0

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The use of a wide variety of materials in the construction of maxillofacial prostheses makes biocompatibility testing a necessity. However, the dental literature contains few reports of biocompatibility testing of maxillofacial prosthetic materials. The cytotoxic profiles of five room-temperature cross-linking (RTC)-silicone elastomers were investigated by means of two in vitro cell culture techniques. Mouse fibroblast cells (L929) were used, and the results indicated that RTC-silicone elastomers adversely affected cells in culture and that storage of samples for 1 week in saline solution did not alter this effect. Clinical follow-up of patients wearing prostheses made of these silicone materials is warranted to evaluate host reactions in long-term contact with human mucous membrane and skin tissue.

引用

页码：505 / 510

页数：6

共 31 条

[1]

CHALIAN VA, 1982, BIOCOMPATIBILITY DEN, V4, P247

[2] ELASTOMERS FOR MAXILLOFACIAL APPLICATIONS [J].