CHEMICAL INVESTIGATION AND ANTIINFLAMMATORY ACTIVITY OF VITEX-NEGUNDO SEEDS

被引：78
作者：
CHAWLA, AS
SHARMA, AK
HANDA, SS
机构：
[1] Department of Pharmaceutical Sciences, Panjab University
[2] Regional Research Laboratory
来源：
JOURNAL OF NATURAL PRODUCTS | 1992年 / 55卷 / 02期
关键词：
D O I：
10.1021/np50080a002
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The CHCl3 extract of the defatted seeds of Vitex negundo exhibited anti-inflammatory activity and yielded four triterpenoids: 3-beta-acetoxyolean-12-en-27-oic acid {1}, 2-alpha,3-alpha-dihydroxyoleana-5,12-dien-28-oic acid {2}, 2-beta,3-alpha-diacetoxyoleana-5,12-dien-28-oic acid {3}, and 2-alpha,3-beta-diacetoxy-18-hydroxyoleana-5,12-dien-28-oic acid {5}. This is the first report of the isolation of compounds 2, 3, and 5 from a natural source.
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页码：163 / 167
页数：5
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