A CASE OF PEUTZ-JEGHERS SYNDROME WITH CARCINOMATOUS DEGENERATION OF A DUODENAL HAMARTOMATOUS POLYP

The authors report a case of Peutz-Jeghers syndrome in a young patient revealed by a duodenal carcinoma developed in a hamartomatous polyp. The absence of a adenomatous lesion a the level of duodenal tumour, and the presence of hamartomatous lesions, particularly smooth muscular fibres, contiguous to carcinomatous glands, are favorable to a degenerescence of harmartomatous polyp. The question of malignant change or of the association of digestive carcinomas is discussed.