Data on the generation of rabbit infections and RPR titre changes in serum samples from syphilis patients at follow-up

被引：1

作者：

Liu, Wen ^{[1
]}

Zhang, Xiaohong ^{[1
,2
]}

Zhao, Tie ^{[1
]}

Zhou, Chenglong ^{[1
]}

Duan, Junxia ^{[1
]}

Zhao, Feijun ^{[1
]}

机构：

[1] Univ South China, Hunan Prov Key Lab Special Pathogens Prevent & Co, Hunan Prov Cooperat Innovat Ctr Mol Target New Dr, Pathogent Biol Inst, Hengyang 421001, Peoples R China

[2] Univ South China, Dept Histol & Embryol, Hengyang Med Coll, Hengyang 421001, Peoples R China

来源：

DATA IN BRIEF | 2018年 / 21卷

基金：

中国国家自然科学基金;

关键词：

Treponema pallidum; Rabbit; RPR; ELISA;

D O I：

10.1016/j.dib.2018.10.075

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The data presented in this article are related to the research article entitled "Performance of novel infection phase-dependent antigens in syphilis serodiagnosis and treatment efficacy determination". The rabbit model [1,2] is an appropriate animal model for studying syphilis, a classic sexually transmitted disease (STD). Live Treponema pallidum (T. pallidum, Tp) and inactivated T. pallidum were inoculated in the backs of New Zealand rabbits. RT-PCR was performed to determine whether T. pallidum DNA could be detected in different groups. Sixty paired serum samples from patients at follow-up were tested by RPR and recombinant Tp0971-, Tp0768-, Tp0462- and Tp92-based ELISA. (C) 2018 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

引用

页码：2237 / 2241

页数：5