MOLECULAR CONNECTIVITY .3. RELATIONSHIP TO PARTITION-COEFFICIENTS

被引：192

作者：

MURRAY, WJ ^{[1
]}

HALL, LH ^{[1
]}

KIER, LB ^{[1
]}

机构：

[1] MASSACHUSETTS COLL PHARM,BOSTON,MA 02115

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1975年 / 64卷 / 12期

关键词：

D O I：

10.1002/jps.2600641216

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1978 / 1981

页数：4

共 12 条

[1]

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HALL, LH ;

KIER, LB ;

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JOURNAL OF PHARMACEUTICAL SCIENCES, 1975, 64 (12) :1974-1977

[3] LINEAR RELATIONSHIPS BETWEEN LIPOPHILIC CHARACTER AND BIOLOGICAL-ACTIVITY OF DRUGS [J].

HANSCH, C ;

DUNN, WJ .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1972, 61 (01) :1-&

[4] LINEAR FREE-ENERGY RELATIONSHIP BETWEEN PARTITION COEFFICIENTS AND AQUEOUS SOLUBILITY OF ORGANIC LIQUIDS [J].

HANSCH, C ;

QUINLAN, JE ;

LAWRENCE, GL .

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[5]

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[6] MOLECULAR CONNECTIVITY .1. RELATIONSHIP TO NONSPECIFIC LOCAL ANESTHESIA [J].

KIER, LB ;

HALL, LH ;

MURRAY, WJ ;

RANDIC, M .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1975, 64 (12) :1971-1974

[7]

KUFFER E, 1969, J MED CHEM, V12, P647

[8] PARTITION COEFFICIENTS AND THEIR USES [J].

LEO, A ;

HANSCH, C ;

ELKINS, D .

CHEMICAL REVIEWS, 1971, 71 (06) :525-+

[9]

NYS GG, 1973, CHIM THER, V5, P521

[10]

RANDIC M, IN PRESS

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