CEREBELLAR MUTISM HAS been reported after surgery for posterior fossa tumors in children and, rarely, in adults. The pathogenesis of this syndrome remains unclear, and controversy exists regarding whether it is a purely psychogenic disorder or an organic syndrome. The anatomical substrate for the mutism also remains unknown. We encountered five cases of postoperative transient cerebellar mutism in a consecutive series of 63 children with posterior fossa tumors. These cases were analyzed and compared with the patients without mutism to find predictive factors for the occurrence of mutism, with the hope of elucidating further the pathophysiological mechanism. The most significant finding was the presence in all cases of a period of cerebellar dysarthria after resolution of the muteness. We, therefore, believe that cerebellar mutism is an extreme form of dysarthria, rather than a real cognitive deficit or a psychological disturbance.
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15254 Shady Grove Rd, Rockville, MD 20850 USA
George Washington Univ, Sch Med, Washington, DC 20052 USA
Childrens Natl Hosp, Washington, DC 20010 USA15254 Shady Grove Rd, Rockville, MD 20850 USA
Walsh, Karin S.
Pizer, Barry
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Alder Hey Childrens NHS Fdn Trust, Dept Paediat Pharmacol, Liverpool, England15254 Shady Grove Rd, Rockville, MD 20850 USA
Pizer, Barry
Samargia-Grivette, Sharyl
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Univ Minnesota, Dept Commun Sci & Disorders, Duluth, MN USA15254 Shady Grove Rd, Rockville, MD 20850 USA
Samargia-Grivette, Sharyl
Lux, Andrew L.
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Bristol Royal Hosp Children, Dept Paediat Neurol, Bristol BS2 8AE, England15254 Shady Grove Rd, Rockville, MD 20850 USA
Lux, Andrew L.
Schmahmann, Jeremy D.
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机构:
Massachusetts Gen Hosp, Ataxia Ctr, Dept Neurol, Cognit Behav Neurol Unit,Lab Neuroanat & Cerebella, Boston, MA USA
Harvard Med Sch, Boston, MA USA15254 Shady Grove Rd, Rockville, MD 20850 USA
Schmahmann, Jeremy D.
Hartley, Helen
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Alder Hey Childrens NHS Fdn Trust, Dept Physiotherapy, Liverpool L12 2AP, England15254 Shady Grove Rd, Rockville, MD 20850 USA
Hartley, Helen
Avula, Shivaram
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机构:
Alder Hey Childrens NHS Fdn Trust, Dept Paediat Pharmacol, Liverpool, England15254 Shady Grove Rd, Rockville, MD 20850 USA
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CHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLICCHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLIC
PARIZEK, J
SERCL, M
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机构:CHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLIC
SERCL, M
MICHL, A
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机构:CHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLIC
MICHL, A
MERICKA, P
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机构:CHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLIC
MERICKA, P
NEMECEK, S
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机构:CHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLIC
NEMECEK, S
NEMECKOVA, J
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机构:CHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLIC
NEMECKOVA, J
JAKUBEC, J
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机构:CHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLIC
机构:
15254 Shady Grove Rd, Rockville, MD 20850 USA
George Washington Univ, Sch Med, Washington, DC 20052 USA
Childrens Natl Hosp, Washington, DC 20010 USA15254 Shady Grove Rd, Rockville, MD 20850 USA
Walsh, Karin S.
Pizer, Barry
论文数: 0引用数: 0
h-index: 0
机构:
Alder Hey Childrens NHS Fdn Trust, Dept Paediat Pharmacol, Liverpool, England15254 Shady Grove Rd, Rockville, MD 20850 USA
Pizer, Barry
Samargia-Grivette, Sharyl
论文数: 0引用数: 0
h-index: 0
机构:
Univ Minnesota, Dept Commun Sci & Disorders, Duluth, MN USA15254 Shady Grove Rd, Rockville, MD 20850 USA
Samargia-Grivette, Sharyl
Lux, Andrew L.
论文数: 0引用数: 0
h-index: 0
机构:
Bristol Royal Hosp Children, Dept Paediat Neurol, Bristol BS2 8AE, England15254 Shady Grove Rd, Rockville, MD 20850 USA
Lux, Andrew L.
Schmahmann, Jeremy D.
论文数: 0引用数: 0
h-index: 0
机构:
Massachusetts Gen Hosp, Ataxia Ctr, Dept Neurol, Cognit Behav Neurol Unit,Lab Neuroanat & Cerebella, Boston, MA USA
Harvard Med Sch, Boston, MA USA15254 Shady Grove Rd, Rockville, MD 20850 USA
Schmahmann, Jeremy D.
Hartley, Helen
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h-index: 0
机构:
Alder Hey Childrens NHS Fdn Trust, Dept Physiotherapy, Liverpool L12 2AP, England15254 Shady Grove Rd, Rockville, MD 20850 USA
Hartley, Helen
Avula, Shivaram
论文数: 0引用数: 0
h-index: 0
机构:
Alder Hey Childrens NHS Fdn Trust, Dept Paediat Pharmacol, Liverpool, England15254 Shady Grove Rd, Rockville, MD 20850 USA
机构:
CHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLICCHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLIC
PARIZEK, J
SERCL, M
论文数: 0引用数: 0
h-index: 0
机构:CHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLIC
SERCL, M
MICHL, A
论文数: 0引用数: 0
h-index: 0
机构:CHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLIC
MICHL, A
MERICKA, P
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h-index: 0
机构:CHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLIC
MERICKA, P
NEMECEK, S
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h-index: 0
机构:CHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLIC
NEMECEK, S
NEMECKOVA, J
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h-index: 0
机构:CHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLIC
NEMECKOVA, J
JAKUBEC, J
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h-index: 0
机构:CHARLES UNIV,FAC MED,DEPT NEUROSURG,CR-50036 HRADEC KRALOVE,CZECH REPUBLIC