ANALYSIS OF ZINC AND OTHER ELEMENTS IN RAT PANCREAS, WITH STUDIES IN ACUTE-PANCREATITIS

被引：12

作者：

KASHIWAGI, M

AKIMOTO, H

GOTO, J

AOKI, T

机构：

[1] Department of Surgery, Jikei University, School of Medicine, Tokyo, 105, 3-25-8, Nishishinbashi, Minato-ku

[2] Department of Textile and Clothing, Kyoritsu Women's University, Tokyo, 101, 2-2-1, Hitotsubashi, Chiyoda-ku

来源：

JOURNAL OF GASTROENTEROLOGY | 1995年 / 30卷 / 01期

关键词：

ACUTE PANCREATITIS; X-RAY FLUORESCENCE; ZINC; ELEMENTS;

D O I：

10.1007/BF01211380

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Determination of the concentration of certain elements makes it possible to investigate the physiology of the pancreas: We used X-ray fluorescence to determine the concentrations of zinc and other elements in the pancreas of normal (control) rats and those with cerulein-induced pancreatitis. Ten elements (Zn, Ni, Fe, P, Ca, Cl, S, K, Ti, and Mn) were detected in controls. In the early stage of acute pancreatitis, the pancreatic concentrations of Zn, Ni, Fe, and P were significantly decreased (P < 0.05) and those of Ca and Cl were significantly increased (P < 0.05), compared with control levels. However, levels of S, K, and Ti did not differ significantly from the control values. Mn was detected in only some samples. The serum levels of Zn and Fe were significantly elevated (P < 0.05) in acute pancreatitis. These observations indicate that Zn and these other nine elements could play an important role in acute pancreatitis.

引用

页码：84 / 89

页数：6

共 24 条

[21]

Ohyanagui Y., SOD and active oxygen modulators, (1989)

[22]

Hempe J.M., Carlson J.M., Cousins R.J., Intestinal metallothionein gene expression and zinc absorption in rats are zinc-responsive but refractory to dexamethasone and interleukin 1α1, J Nutr, 121, pp. 1389-1396, (1991)

[23]

Smith M.L., Fariss B.L., Jennings P.B., Serum zinc levels in sheep with experimental pancreatic abnormalities, Pancreas, 1, pp. 20-23, (1986)

[24]

Boosalis M.G., Evans G.W., McClain C.J., Impaired handling of orally administered zinc in pancreatic insufficiency, Am J Clin Nutr, 37, pp. 268-271, (1983)

← 1 2 3 →