HIGH-FREQUENCY INTERGENOMIC RECOMBINATION OF SUID HERPESVIRUS-1 (SHV-1, AUJESZKYS-DISEASE VIRUS)

被引：18
作者：
CHRISTENSEN, LS
LOMNICZI, B
机构：
[1] STATE VET INST VIRUS RES, LINDHOLM, DENMARK
[2] HUNGARIAN ACAD SCI, VET MED RES INST, H-1361 BUDAPEST 5, HUNGARY
来源：
ARCHIVES OF VIROLOGY | 1993年 / 132卷 / 1-2期
关键词：
D O I：
10.1007/BF01309842
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Examples are given of observations made with field isolates of suid herpesvirus 1 (SHV-1) which indicate that intergenomic recombination is a common phenomenon associated with the virus. This was further confirmed by experimental co-infection of a pig with 2 virus strains with different, stable and easily identifiable genomic markers, followed by natural transmission to a group of contact pigs. A variety of recombinants was subsequently isolated, while none of the parental strains were re-isolated from any of the pigs. It is suggested that co-invasion of cells and recombination between viral genomes play a role in the life cycle of the virus.
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页码：37 / 50
页数：14
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