ESTABLISHMENT OF AN IL-2-DEPENDENT, ANTIGEN NONSPECIFIC CHICKEN T-CELL LINE

被引：17
作者：
CORBEL, C [1 ]
THOMAS, JL [1 ]
机构：
[1] COLL FRANCE,NOGENT SUR MARNE,FRANCE
来源：
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY | 1990年 / 14卷 / 04期
关键词：
Chicken; Interleukin; 2; T lymphocyte;
D O I：
10.1016/0145-305X(90)90036-E
中图分类号：
S9 [水产、渔业];
学科分类号：
0908 ;
摘要：
In this article, we describe a-chicken T helper-activated cell line, III-C5, which is non-antigen-specific but IL-2-dependent. By virtue of its absolute requirement for IL-2, the III-C5 cell line is a useful tool for quantifying IL-2 production by any chicken-activated T lymphocytes in culture. The III-C5 line will be used to quantify IL-2 production in mixed lymphocyte reaction in vitro, in order to study the functional activity of T lymphocytes from avian chimeras constructed in our laboratory and particularly for studying their state of tolerance. © 1990.
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收藏
页码：439 / 446
页数：8
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